Ventana Medical Systems, Inc.

Brian Howard Kram

Kevin David Marshall

Christine Tse

Henning Groll

Austin Micheil Ashby

Michael Otter

Glen Ward

Simon Jonathon Spence

Matthew Ketterer

Matthew Mette

Donald Michael Barnett

Benjamin James

Benjamin David Randall

Daniel O'Connor

Carl David Martin

Christopher Bieniarz

Paul D Drumheller

Chad Wilkinson

Timothy James Keller

Timothy Durrant

Timothy Brett McDonald

Edward E Durrant

Casey A Kernag

Josh Harrison

John Douglas Willems, Jr

Melinda Polaske

Charles Daniel Lemme

William L Richards

Wayne A Showalter

David Chafin

Andrew Ghusson

Anthony L Hartman

Vincent R Rizzo

David Bryant

Nathan Crum

Kevin Talucci

Ryan J Reeser

Catherine Wolf

Evan T Graves

Ken Stumpe

Troy Paluszcyk

Ali Mousavi

Kayla Capps

Joshua David Kenneth Harrison

Luke Dyson-Holland

Daniel C Malberg

Charles H Weidner

Christian Roessler

Jessica Jones

Jessica A Wifall

Heidi Barnett

Zofia Wosinska

Kristina Orosz

Mirek Holubec

James E Phillips-Portillo

Samuel Psota

Daniel Champion

Kenneth S Weir

Sacha Marie Dopheide

John Willems

Sacha Dopheide

Andrew Watkins

Bryan Barnes

Lizhen Pang

Patrick Brown

Alastair Laing

Randy Stephens

Daniel R Kurycki

Daniel O`connor

Charles Weidner

Edward Durrant

Jr John D Willems

Matthew D Mette

Chad A Wilkinson

Daniel O`CONNOR

Automated system configured to perform and methods for performing one or more slide processing operations on slides bearing biological samples. The system and methods enable high sample throughput while also minimizing or limiting the potential for cross-contamination of slides. The automated systems can include features that facilitate consistency, controllability of processing time, and/or processing temperature.

Automated histological processing of biological specimens and associated technology

At least some embodiments of the technology are directed to an automated slide processing apparatus configured to apply at least one reagent to a specimen carried by a microscope slide. The slide processing station can include a support element with a support surface, at least one vacuum port, and a sealing member having a non-round shape. In an uncompressed state, the scaling member can extend upwardly beyond the support surface. In a compressed state, the scaling member can be configured to maintain an airtight seal with a backside of the microscope slide as the microscope slide is pulled against the support surface by a vacuum drawn via the at least one vacuum port.

Specimen processing systems and methods for holding slides

At least some embodiments of the technology are directed to an automated slide processing apparatus configured to apply at least one reagent to a specimen carried by a microscope slide. The slide processing station can include a support element with a support surface, at least one vacuum port, and a sealing member having a non-round shape. In an uncompressed state, the sealing member can extend upwardly beyond the support surface. In a compressed state, the sealing member can be configured to maintain an airtight seal with a backside of the microscope slide as the microscope slide is pulled against the support surface by a vacuum drawn via the at least one vacuum port.

Disclosed are specimen processing systems capable of processing specimens carried on slides. The specimen processing systems comprise opposables having at least one fluid control element. The fluid control elements may be positioned between spacers or gapping elements the opposable edges. The fluid control elements may comprise an edge, such as a beveled edge or a stepped edge, as described herein, and the edge may be continuous or segmented.

Opposables incorporating fluid control elements and automated specimen processing systems

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures. The applied liquid can be in a fluid-carrying gap. The opposable can contact the slide to vary a cross section of the fluid-carrying gap.

Opposables and automated specimen processing systems with opposables

Processing specimens in an automated histological staining system comprising robotically moving a slide carrier into a stainer of the system, the slide carrier carrying slides which respectively carry the specimens, and the specimens being at least partially embedded in paraffin. Liquids are automatically dispensed onto the slides according to a predetermined recipe for at least deparaffinizing, staining, and counterstaining the specimens. The slide carrier can be robotically moved out of the stainer after automatically dispensing the liquids. In some embodiments, a total of all liquid dispensed onto the slides after moving the slide carrier into the stainer and before moving the slide carrier out of the stainer has a greater volumetric concentration of polyol than of monohydric alcohol.

Staining reagents and other liquids for histological processing of biological specimens and associated technology

A specimen processing system is capable of processing specimens carried on slides. The specimen processing system can sequentially deliver slides and opposables to specimen processing stations. The specimen processing stations can use the opposables to apply a series of liquids to the specimens. The applied liquid can be moved along the slide using capillary action while the specimen processing stations control the processing temperatures.

Specimen processing systems and methods for aligning slides

An embodiment of the method of the invention is a method of automating information flow in a laboratory performing tissue staining comprising positioning a networked label printer adjacent to a cutting station, the printer configured to access patient data directly or indirectly from the hospital LIS, the printer being configured with a data element scanner in electronic communication with said printer; inputting data from a tissue cassette-associated data element at said printer, whereby inputting data comprises reading the data from the cassette-associated data element and uploading the cassette data to the LIS; identifying the corresponding test protocol identifier and then downloading the test protocol data to the printer; printing information on labels corresponding to each test specified in the LIS for the patient; attaching a single label to each slide; and cutting a tissue section for each labeled slide and mounting the section on the slide.

Automated lean methods in anatomical pathology

An apparatus can be used to apply and remove fluid substances for processing biological samples. The fluid substances can be delivered between a first substrate and a second substrate. One substrate carries a specimen. A layer of the fluid substance is retained in a gap defined by the first and second substrates. One substrate is moved with respect to the second substrate to disperse the fluid substance in the gap.

Thin film processing apparatuses for adjustable volume accommodation

Arcuate member for moving liquids along a microscope slide

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Tucson, AZ, United States of America

Brian Howard Kram