Emd Millipore Corporation

Millipore Corporation

Brian Hillier

Matthew Natale

Aaron Burke

Joseph M Almasian

Martin Szyk

Joseph Geringer

Stephen Proulx

John Paul Amara

Jeremy Perreault

David DeCoste

Joseph William Muldoon

Michael James Susienka

Stephen P Proulx

A filtration module is provided, the module including at least one filtration packet containing filtration media or one or more membranes, such as a stack of membranes, the at least one filtration packet having one or more fluid ports, the one or more fluid ports being surrounded by a primary seal and a secondary seal spaced from the primary seal. The secondary seals are designed to maintain sterility of the assembly during shipping, handling and/or installation. A removable film may cover one or more fluid ports to maintain sterility prior to use.

Closed bioprocessing device

A sealing case for a filtration cassette that reliably prevents leaks after assembly and installation into a filtration system. The sealing case fits on the filtration cassette and provides a fluid-tight seal between the sealing case and around at least one port in the filtration cassette when installed in a filtration system. The sealing case may comprise two halves that mate together, and each half may be identical. The internal surface of the sealing case is flat or substantially flat.

Sealing case for filter cassette

Retentate plate

Diverter plate

Fluid transfer apparatus including a body having a bore formed through at least a portion of its interior. Contained within the bore is a movable plunger that moves without changing the axial dimensions of the body. A first end of the body contains a face designed to be attached to an upstream component. A second end of the body is connected to a downstream component such as a filter, pipeline, etc. A first end of the plunger, when it is in the closed position, is in alignment with the face of the body, which combined form a steamable surface and a sterile barrier against the environment to the remainder of the interior of the body, the plunger and downstream components. An outer annular collar is rotatable relative to the body and causes the plunger to move axially within the bore from an open to a closed position.

Fluid transfer device and system

A method for over-molding a tubular filter element, at least at one endthereof, with a thermoplastic end cap. The over-molding method can be used to manufacture easily and cost-effectively a filter cartridge, of good durability, from an unprecedented range of polymeric materials and components. The thermoplastic over-molding method does not require pre-lamination of said end, and can be performed at temperatures and pressures that do not result in undesirable morphological changes in the tubular filtration medium. Exemplary filter cartridges made through the over-molding method comprise a tubular filtration medium interposed between thermoplastic end caps, the thermoplastic material of the end caps infiltrating the tubular filtration medium, thereby creating mechanical interlock zones at the ends thereof.

Thermoplastic injection molding method for capping a tubular filtration medium

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Billerica, MA, United States of America

Brian Hillier