Neurometrix, Inc.

Hypermed Imaging, Inc.

Brian H Tracey

Srivathsan Krishnamachari

Shai N Gozani

Jenny E Freeman

Xuan Kong

Michael J Hopmeier

Michael L Williams

Svetlana Panasyuk

Alexander Panasyuk

Svetlana V Panasyuk

Alexander A Panasyuk

The present invention provides a hyperspectral imaging system which demonstrates changes in tissue oxygen delivery, extraction and saturation during shock and resuscitation including an imaging apparatus for performing real-time or near real-time assessment and monitoring of shock, including hemorrhagic, hypovolemic, cardiogenic, neurogenic, septic or burn shock. The information provided by the hyperspectral measurement can deliver physiologic measurements that support early detection of shock and also provide information about likely outcomes.

Hyperspectral/multispectral imaging in determination, assessment and monitoring of systemic physiology and shock

A method for the automated removal of a stimulus artifact from an electrophysiological signal waveform, wherein the novel method comprises:

Automated stimulus artifact removal for nerve conduction studies

A method for the assessment of neuromuscular function by the detection and classification of late wave activity, comprising: (i) pre-processing an ensemble of traces so as to attenuate noise, PFI and baseline disturbances; (ii) identifying time segments of late wave activity in the ensemble of traces; (iii) classifying the time segments of late wave activity into F-wave, A-wave and Repeater segments by exploiting the variable morphology of F-waves across the traces and the fixed morphology of A-waves and Repeater waves across the traces; and (iv) searching the traces in the vicinity of the F-wave trace segments on a trace-by-trace basis so as to identify the F-wave onset latency.

Detection and classification of neuromuscular late wave activity for the assessment of neuromuscular function

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Arlington, MA, United States of America

Brian H Tracey