Becton Dickinson and Company Limited

Brian G Scrivens

Dwight Livingston

Klaus W Berndt

Robert S Frank

Timothy Roy Hansen

Jeffrey P Andrews

Christian V O'Keefe

Willard C Pope

Frank L Failing

The present invention relates to a method and apparatus for analyzing a blood or other biological fluid sample in a quiescent state, whereby particulate constituents of biological samples that contain sparse populations of interesting cellular species can be enumerated and inspected using an optical scanning instrument. Specifically, this invention relates to a method and apparatus for obtaining increased cellular or particulate concentrations within the use of said optical scanning method.

Method for obtaining increased particle concentration for optical examination

The present invention relates to a method and apparatus for analyzing a blood or other biological fluid sample in a quiescent state without the need for additional diluting reagents or fluid streams passing through the apparatus during the analytic process, whereby particulate constituents of biological samples can be enumerated and inspected using an optical scanning instrument. Specifically, this invention relates to a method and apparatus for obtaining decreased cellular or particulate concentrations within the use of this system.

Method for obtaining a monolayer of desired particles in a liquid sample

Apparatus for obtaining increased particle concentration for optical examination

The present invention relates to the field of diagnostics by means of microscopic sample analysis, and specifically relates to a method and apparatus for preparing thin microscopic samples of liquids, and in particular monolayers of red blood cells.

Apparatus for producing thin liquid samples for microscopic analysis

An apparatus and method employing a plurality of light emitting devices which each can get light through a respective optical fiber toward a respective sample of a plurality of samples in a time-staggered manner. Light is generated in each of the samples at different times consistent with the times at which light is irradiated onto the sample. A single detector is used to detect the lights emitted from the plurality of samples at these different times. A plurality of bifurcated optical cable are coupled to the light emitting devices and single light detector, and the integrated end of each bifurcated cable acts as the light emitting port and light detecting port. Multiple targets can be detected from each of the plurality of samples in the same manner by providing an apparatus and method employing a different plurality of light emitting devices and single detector for each target to be detected.

Automated Optical Reader for Nucleic Acid Assays

Method for producing thin liquid samples for microscopic analysis

An apparatus and method employing a plurality of light emitting devices which each can get light through a respective optical fiber toward a respective fluid sample of a plurality of fluid samples in a time-staggered manner. Light is generated in each of the fluid samples at different times consistent with the times at which light is irradiate onto the sample. A single detector is used to detect the lights emitted from the plurality of samples at these different times. A plurality of bifurcated optical cable are coupled to the light emitting devices and single light detecting device, and the integrated end of each bifurcated cable acts as the light emitting port and light detecting port.

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Colora, MD, United States of America

Brian G Scrivens