Lawrence Livermore National Security, LLC

Brian E Souza

Matthew A Coleman

Feliza A Bourguet

Paul J Jackson

Carlos A Valdez

Bonnee Rubinfeld

Lawrence Dugan

Roald N Leif

Mathew Gerald Lyman

Targeted antimicrobials are described and related, compositions, methods and systems.

Targeted antimicrobials and related compositions, methods and systems

Biodegradable surfactants are described, in which an amphiphilic heteroatom containing hydrocarbon optionally comprising at least one counterion (Z), and related compositions, methods and systems. Biodegradable surfactant described herein has an aHLB value in accordance with equation (1): aHLB=20*Gh/(Gh&#x2212;Gt) (1) wherein Gh is the Group Number of a hydrophilic head portion of the biodegradable surfactant optionally comprising the at least one counterion (Z), and Gt is the Group Number of a hydrophobic tail portion of the biodegradable surfactant. A biodegradable surfactant in the sense of the disclosure can be tuned to a set hydrophilic-lipophilic balance (aHLB) by selectively modifying at least one tuning moiety of the biodegradable surfactants to provide tuned biodegradable surfactants having an increase or decrease in their adjusted hydrophilic-lipophilic balance (aHLB).

Biodegradable surfactants and related compositions, methods and systems

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Livermore, CA, United States of America

Brian E Souza