Koninklijke Philips Corporation N.v.

Brian David Gross

Larry Nielsen

Mohammed Saeed

Joseph James Frassica

Elizabeth J Zengo

Soren Steiny Johnson

Larry James Eshelman

Ivan Salgo

Kwok Pun Lee

Abigail Acton Flower

Wei Zong

Nicolaas Lambert

Yuechen Qian

Ihor Olehovych Kirenko

Merlijn Sevenster

Saeed Babaeizadeh

Wilhelm Meier

John Blair

Jyh-Yun John Wang

Gerhard Tivig

Stijn De Waele

Ayman Alalao

Daniel A Silber

Yugang Jia

Henry Lin

Guenter Gegner

Thomas Andre Forsberg

Bastiaan Feddes

Bernd Wilm

Eran Rubens

Colleen Michelle Ennett

Pradyumna Dutta

Hanqing Cao

Volker Manfred Hubert

Qianxi Li

Robert A Feuersanger

Gregory Raber

Andrew Franklin Arthur

W Scott Reid

Martin Bufe

Benedikt Latz

Axel Joachim Lange

Robert Alfred Feuersanger

David L Feer

David Warren Weiss

Suzanne Kavanagh

Erik Johnson

Dale Wiggins

Marcus Holland-Moritz

Jan Wittenber

Charles Lagor

Monroe Wyatt Pattillo

Robert Duane Porterfield

Redvers Curtis Gosse

John Louis Barga

Larry James Eschelman

Davy Hin Tjiang Tjan

David Youngjin Kim

Andreas Pirrung

Dmitri Shvartsman

Eric D Nelson

Issac Eldo

Thomas Chou

Erik E Johnson

Gregory H Raber

Provided herein are computer implemented methods, systems and processes for determining a transmission metric or transmission path for related pathogens. Also provided herein is a non-transitory computer-readable storage medium with an executable program stored thereon, which program is configured to instruct a microprocessor to generate a transmission path for related pathogens.

Methods, systems and processes of determining transmission path of infectious agents

A method for prioritizing sequencing of nucleic acid molecules from two or more sources, comprising: (i) ligating one or more ends of each of a plurality of nucleic acid molecules to an adapter, wherein the adaptor is unique to each source and comprises a unique identifier nucleic acid sequence; (ii) pooling the nucleic acid molecules from each of the two or more sources; (iii) sequencing a plurality of nucleotides of an identifier nucleic acid sequence of an adapter; (iv) determining in real-time from which of the two or more sources the nucleic acid molecule being sequenced came; (v) determining, from a prioritization rule set and based on the determined source, a sequencing priority for the nucleic acid molecule; and (vi) allowing the sequencing process to proceed, or modifying the sequencing process, based on the determined sequencing priority.

System and method for real-time prioritization of sequencing

A clinical therapy system () includes a drug delivery device () configured to delivery medication to a patient. One or more therapy devices () are configured to provide therapy or to monitor the patient. A computer () is programmed to perform a CDS method () including: receiving clinical context data for the patient from a health information system (HIS) (); receiving high fidelity data () comprising real time measurements for the patient from one or more of the drug delivery device, one or more vital sign sensors, and at least one device of the one or more therapy devices; applying one or more physiologic models () to the combination of the clinical context data and the high fidelity data to generate a clinical prediction for the patient; outputting a therapy recommendation for the patient based on the clinical prediction for the patient; and controlling operation of the drug delivery device or one of the therapy devices based on the therapy recommendation.

System and method for joint clinical decision for pharmaceuticals

A method for processing sequencing data, including: (i) generating, by a sequencing platform, a plurality of sequencing signals from a sequencing operation, each of the plurality of sequencing signals representing a genetic sequence; (ii) sampling, by a controller, each of the plurality of sequencing signals at a Nyquist rate of the sequencing platform to generate an upsampled signal; (iii) receiving, for each of the plurality of sequencing signals, the respective upsampled signal and information associated with the respective sequencing signal, comprising a base pair read number and a time stamp for the respective sequencing signal; (iv) packaging, by the controller for each sequencing signal, the received upsampled signal, base pair read number, and time stamp into a data packet; (v) organizing the packaged data packets into a multiplexed single data stream; and (vi) transmitting the multiplexed single data stream to a remote system.

Compression and annotation of digital waveforms from serial read next generation sequencing to support remote computing base calling

A patient monitor () includes a display (). Patient values () are obtained for one or more known variables of a risk prediction function (). One or more unknown variables of the risk prediction function are determined, and at least one hyperplane () is defined as values assumable by the one or more unknown variables. Values of the risk prediction function are computed over the at least one hyperplane using the obtained patient values. A visualization template is selected from a database of visualization templates () using template selection indices including the risk prediction function and the one or more unknown variables. Using the visualization template, a visualization () of the computed values of the risk prediction function over the at least one hyperplane is displayed.

Contextualized patient-specific presentation of prediction score information

In a medical workspaces management method, a user identified in a users database () is authenticated. At a server computer (), a virtual session is created including running instances () of a plurality of medical applications on the server computer with the instances associated with the authenticated user. Using at least one locating service (), a current medical content presentation device () is identified which is proximate to the authenticated user. At the server computer, a set of rules is applied to determine content of the instances to be presented. This content is pushed from the server computer to the current medical content presentation device. At the current medical content presentation device, the pushed content is presented on a display () of the current medical content presentation device.

System and method for optimizing a user experience based on patient context, user roles, current workflow, and display proximity

The medical system and method detect arrhythmic events. The medical system includes at least one processor programmed to perform the method. A photoplethysmogram (PPG) signal generated using a PPG probe positioned on or within a patient and a pulse signal generated using an accelerometer positioned on or within the patient received. Features from the PPG signal are extracted to PPG feature vectors, and features are extracted from the pulse signal to pulse feature vectors. The PPG feature vectors are correlated with the pulse feature vectors, and correlated PPG feature vectors and correlated pulse feature vectors are evaluated to detect arrhythmic events.

System and method to detect significant arrhythmic events through a photoplethysmogram (PPG) and accelerometer

A medical device and caretaking management system () includes a plurality of medical devices () that transmit equipment data and patient data. A central or distributed monitoring system () receives the equipment data and patient data from the plurality of medical devices, derives an acuity for each of the patients, and assigns caregivers and equipment based on the derived acuity for display on a display device ().

System and method for providing medical caregiver and equipment management patient care

Each sensor of a plurality of sensors operates independently to perform at least a monitoring function acquiring sensor data indicative of a common physiological parameter and a grading function performed occasionally to assign a current signal quality grade for the sensor that is indicative of operational status of the monitoring function of the sensor. A data structure stores information pertaining to the plurality of sensors including at least priorities of the plurality of sensors respective to the common physiological parameter and the current signal quality grades for the sensors. Each sensor further operates to perform at least one output function generating an output signal conditional upon content of the data structure including at least the priorities and the current signal quality grades of the sensors indicating the output function should be performed.

Body worn sensors network with redundant parameter prioritization and temporal alignment

A movement and/or a position of an object () to be monitored is detected. At least one marker () radiating light is arranged in an area of the object () such that a camera () can capture images of the marker (), when the object () is in a first position. An image processing unit () is enabled to detect the marker () in the images and to detect a movement and/or a second position of the object () in response to determining that at least a part of the marker () cannot be detected in one or more of the images. The object () may be a person laying in a bed and the marker () may be arranged adjacent to the bed's lying area () so that the system can detect when the person leaves the bed and notify nursery staff or an emergency central.

Detecting a movement and/or a position of an object to be monitored

A method for controlling access to data being processed by a remote computing resource includes issuing a public encryption key for a data creator from a public certificate authority, detecting an encounter with a data owner, creating private encryption keys for the data creator and the data owner in response to detecting the encounter, encrypting data being sent to the remote computing resource with the public encryption key, the data creator's private encryption key, and the data owner's private encryption key, decrypting the data based on public verification of the public encryption key and local verification of the data creator's private encryption key and the data owner's private encryption key at the remote computing resource, and controlling the data creator's access to the data by altering the permission of at least one of the public encryption key and data creator's private encryption key.

Controlling access to clinical data analyzed by remote computing resources

A method of monitoring a patient includes receiving patient data from one or more sensors a patient monitoring system, comparing the received patient data with preselected thresholds indicative of patient status, determining a patient status from comparing the received patient data with the preselected thresholds, and adjusting a sampling frequency of the one or more sensors based on the determined patient status.

System and method for optimizing the frequency of data collection and thresholds for deterioration detection algorithm

A system for making data source anonymous including a plurality of data sources, each data source including a data creation engine which creates normalized data in accordance with a common schema and a transformation engine which de-normalizes the normalized data such that the data source cannot be inferred by other data sources and transmits the de-normalized data to a remote computing resource. A remote computing resource receives and stores the de-normalized data from the plurality of data sources.

Method and system for making multisite performance measure anonymous and for controlling actions and re-identification of anonymous data

A room monitoring system includes a plurality of in-room units. The in-room units collect information relating to a clean or dirty status of a plurality of patient rooms and/or equipment in the rooms. A monitoring station receives clean or dirty status information from the in-room units and determines which rooms are clean, and ready for a patient, which are dirty and in need of cleaning, and which are occupied.

Method and system to detect that a device has been cleaned

A method includes obtaining an electrical signal that includes a set of at least two sensed physiologic measurements of a patient, comparing the at least two physiologic measurements with a predetermined physiologic measurement range, identifying data required to determine a probability and a severity of a condition of interest of the patient, in response to determining the at least two physiologic measurements do not satisfy the physiologic measurement range, receiving the identified data in electronic format, determining a first probability and a first severity of the condition of interest based on the received identified data, determining a recommended course of action for the patient based on the first probability and the first severity, resources of a healthcare facility, and an event guideline; and causing a display to visually present the first probability and first severity and the recommended course of action.

Clinical decision support system based triage decision making

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North Andover, MA, United States of America

Brian David Gross