Cook Medical Technologies LLC

Med Institute Incorporated

Cook Incorporated

Other

Medical Engineering and Development Institute, Inc.

Benjamin Nickless

Charles W. Agnew

Richard S. Sisken

Brian D. Choules

Brian D Choules

Neal E Fearnot

Brian L Bates

Anthony O Ragheb

James D Purdy

William J Bourdeau

Charles W Agnew

Keith Milner

Joseph M Stewart, Iv

Richard B Sisken

Michael P DeBruyne

Sara Marie Sherman

Matthew S Waninger

Richard S Sisken

Joseph M Stewart

A coated medical device () including a structure () adapted for introduction into a passage or vessel of a patient. The structure is formed of preferably a non-porous base material () having a bioactive material layer () disposed thereon. The medical device is preferably an implantable stent or balloon () of which the bioactive material layer is deposited thereon. The stent can be positioned around the balloon and another layer of the bioactive material posited over the entire structure and extending beyond the ends of the positioned stent. The ends of the balloon extend beyond the ends of the stent and include the bioactive material thereon for delivering the bioactive material to the cells of a vessel wall coming in contact therewith. The balloon further includes a layer of hydrophilic material () positioned between the base and bioactive material layers of the balloon.

Coated medical device

Disclosed is an anchoring element for an implantable prosthesis that includes a barb, wherein the anchoring element, which includes a basal portion, comprises a thin layer of material, such as a cannula or sheet of metal, that extends or wraps at least partially around the strut of the prosthesis to which it is attached. The barb is configured to extend outward from the basal portion to penetrate adjacent tissue. The anchoring element is either permanently affixed to the strut, such as by laser or spot welding, crimping, or some other method of bonding, or allowed to slide longitudinally over the strut between two points or stops in order to relieve any excessive loads placed upon the barb that could cause fracture. The anchoring element and strut may be configured to limit axial rotation of the barb, while still allowing longitudinal movement. In another embodiment, the slidable anchoring element may be manipulated following initial deployment to reorient the barb toward the implantation site.

Anchoring barb for attachment to a medical prosthesis

A medical prosthesis for implantation within the body of a patient comprises a support structure and an anchoring element that comprises a basal portion and at least one barb extending from the basal portion. The anchoring element may be slidably attached to the strut and the strut may include a first stop and a second stop that define a longitudinal zone of movement for the anchoring element. Other devices and methods are described.

A medical device () includes a structure () adapted for introduction into a patient, the structure () being formed of a preferably non-porous base material () having a roughened or textured surface (). The structure () is conveniently configured as a vascular stent with a base material () of stainless steel, nitinol or another suitable material. The medical device () also includes a layer () of a bioactive material posited directly upon the roughened or textured surface () of the base material () of the structure (). The surface () of the base material () is roughened or textured by etching or by abrasion with sodium bicarbonate or another suitable grit. A preferred roughened or textured surface () is thought to have a mean surface roughness of about 10 &#x3bc;in. (about 250 nm) and a surface roughness range between about 1 &#x3bc;in. and about 100 &#x3bc;in. (about 25 nm and about 2.5 &#x3bc;m). The particularly preferred use of sodium bicarbonate as the abrasive to provide roughness or texture to the surface () of the base material () of the structure () is additionally advantageous in the low toxicity of the sodium bicarbonate to production workers, the ease of product and waste cleanup, and the biocompatibility of any residual sodium bicarbonate.

Coated implantable medical device

An expandable stent prosthesis is disclosed in which the apices of the bends located at at least one end of the stent are individually twisted at an angle to the circumference of the stent to form a fan blade-like arrangement when viewed from that end. The fan blade-like arrangement allows the stent to expand from the compressed condition during deployment such that likelihood of a strut or bend of the stent become entangled with a barb or adjacent strut or bend, is reduced. In one embodiment of the invention, the fan blade-like arrangement results from plastically deforming the individual apices, while in another embodiment, the apices are twisted into the fan blade-like arrangement during the loading process, such as by use of a suture thread to pull the apices into alignment.

Stent adapted for tangle-free deployment

Growing community of inventors

Washington, UT, United States of America

Brian D Choules