Advanced Technologies and Regenerative Medicine, LLC

Ethicon, Gmbh

Depuy Synthes Products, Inc.

Brian C Kramer

Sanjay Mistry

Darin J Messina

L S Klaudyne Hong

Michael J Romanko

Anna Gosiewska

Agnieszka Seyda

David C Colter

Charito S Buensuceso

Anthony J Kihm

Uri Herzberg

Laura J Brown

Provided are therapeutic implants comprising renal tissue encapsulated within a polymer bead. Also disclosed are methods for treating a disease state in a subject comprising implanting within said subject a therapeutic implant comprising renal tissue encapsulated within a polymer bead. Also provided are methods for making a therapeutic implant comprising: providing renal tissue; mixing the renal tissue with a solution comprising a polymer, thereby forming a tissue-polymer suspension; extruding the tissue-polymer suspension into an bead-forming solution, thereby forming a therapeutic implant comprising beads of said polymer within which the renal tissue is encapsulated.

Encapsulated kidney tissue

This invention relates to methods of treating stroke by intranasal administration of umbilical cord tissue-derived cells, which are isolated from mammalian umbilical cord tissue substantially free of blood or expanded in culture from a cell isolated from mammalian umbilical cord tissue substantially free of blood, are capable of self-renewal and expansion in culture, and do not produce CD117 and/or telomerase. The methods of the invention regenerate, repair and improve neural tissue and improve behavior and neurological function in stroke patients.

Treatment of stroke and other acute neural degenerative disorders via intranasal administration of umbilical cord-derived cells

Cells derived from postpartum tissue such as the umbilical cord and placenta, and methods for their use to regenerate, repair, and improve neural tissue, and to improve behavior and neurological function in stroke patients are disclosed.

Treatment of stroke and other acute neural degenerative disorders using postpartum-derived cells

Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to treat patients having a neurodegenerative condition of the substantia nigra or striatum, such as Parkinson's disease, are provided.

Treatment of Parkinson's disease and related disorders using postpartum derived cells

Treatment of stroke and other acute neuraldegenerative disorders using postpartum derived cells

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Plainfield, NJ, United States of America

Brian C Kramer