Bioelectromed Corporation

Brian Athos

Richard Lee Nuccitelli

Pamela S Nuccitelli

Saleh Sheikh

Suman Narsing

Mark P Kreis

Shr-Kai Liau

Kevin Tran

Uwe F Pliquett

Changyi Li

The present invention provides a hand-held, noninvasive diagnostic device for measuring the electric fields in mammalian skin and other epithelial structures. The device includes an outer housing that contacts the skin, providing stability and allowing the device to move along with minor movement of the skin. Recessed within the outer housing is a probe that acts as a sensor to measure the electric field in the skin through an aperture in the bottom surface of the outer housing. By applying a series of known voltages while the probe is vibrating, the skin's local surface potential can be measured and the lateral electric field can be calculated from the spatial distribution of surface potential measurements. Active feedback is used to maintain a constant distance between the probe and the skin surface.

Hand-held electric field imager for measuring the electric field in mammalian skin and other epithelial structures

Hand-held electric field imager for measuring the surface topography of mammalian skin and other epithelial structures

Nanosecond pulsed electric field (nsPEF) parameters for destroying tumors with a single treatment are described. A nsPEF generator may be used with an electrode assembly to apply the pulses to one or more tumors where the parameters for the nsPEF are optimized for treating such tumors.

Nanosecond pulsed electric field parameters for destroying tumors with a single treatment

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Pleasanton, CA, United States of America

Brian Athos