Novartis Ag

Brian Addison DeChristopher

Andrew John Geall

Luis Brito

Rohan Eric John Beckwith

Thomas Zabawa

Gabriel Grant Gamber

This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R, R, Rand Rare defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.

Lipids and lipid compositions for the delivery of active agents

This invention provides for a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein R, R, Rand Rare defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues. 

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Cambridge, MA, United States of America

Brian Addison DeChristopher