Ellodi Pharmaceuticals, L.p.

Purdue Pharma L.p.

Adare Pharmaceuticals, Inc.

Brian A Meltzer

Gail M Comer

Gina Eagle

Sayee Natarajan

The present disclosure provides methods of treating inflammation of the upper gastrointestinal tract, especially the esophagus, by administering an oral corticosteroid. In some cases, the methods include treating eosinophilic esophagitis (EoE) by administering an oral corticosteroid in an induction phase and a maintenance phase to improve peak eosinophilic counts and symptoms. In embodiments, the methods include treating EoE by administering the oral corticosteroid at nighttime and/or while the patient is lying down.

Methods of treating eosinophilic esophagitis

A method in support of health management services acts upon active and passive data, in which the active data is communicated by a patient or healthcare professional and in which the passive data is detected by at least one sensor detectably coupled to the patient. These data are correlated with each other and if a predefined correlation is not met, further data can be solicited, patient-specific queries can be generated, alerts can be communicated, or a combination of these can be done in embodiments of the invention. Any Irregularity or trend in the data can be identified and processed in embodiments of the invention. Also in some embodiments, these data can be used in connection with intelligent, machine-based decisions to send communications concerning the provision of further healthcare resources to patients, such as in view of their relative acuity rank. Systems can be constructed to implement the methods described herein.

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Wilton, CT, United States of America

Brian A Meltzer