Galaxy Therapeutics Inc.

Neodyne Biosciences, Inc.

Progressive Neuro, Inc.

Covidien LP

Fox Hollow Technologies, Inc.

Medtronic, Inc.

Cardiac Pathways Corporation

Depuy Synthes Products, Inc.

Tyco Healthcare Group LP

Avantec Vascular Corporation

Neodyne Bioscience, Inc.

Brett Allen Follmer

Arturo S Rosqueta

Darren G Doud

Thomas J Wolfe

Osama O Zaidat

Aamir Badruddin

Edgard Luiz Ramos Pereira

Jasper Jackson

John A Zepeda

William R Beasley

John B Simpson

Michael H Rosenthal

Himanshu N Patel

Greg Stine

Geoffrey C Gurtner

Richard S Lilly

Stephen W Boyd

Keiichiro Ichiryu

Paul G Yock

Mehrdad Farhangnia

Adam French

Kemal Levi

Tor C Krog

Manuel A Cardona Pamplona

Mir A Imran

David W Snow

William Stephen Tremulis

Mark L Pomeranz

Brian A Glynn

Tiffany Tran Ngo

John G Stine

Edward M Gillis

Tim Corvi

Kirk Zeller

Andrew Huffmaster

Karl Halden

Erin McGurk

Eric Willis

Edward F Ruppel

Ryan M Hoshino

Nicholas C deBeer

Sheila Vallesteros Asuncion

Farhangnia Mehrdad

Adam C French

Karl Sterling Halden

Andrew Scott Huffmaster

Nicholas Debeer

An apparatus for treating an aneurysm includes an occlusion element configured to be releasably coupled to an elongate delivery shaft and having a distal end, a proximal end, and a longitudinal axis extending between the distal end and the proximal end, the occlusion element configured to be delivered in a collapsed configuration and further configured to expand to an expanded configuration, the occlusion element comprising an inverted mesh tube having an outer layer and an inner layer, the outer layer transitioning to the inner layer at an inversion fold located at or adjacent the distal end of the occlusion element, the inversion fold defining an inner diameter, the occlusion element further comprising a maximum outer diameter, wherein the inner diameter is between about 35% to about 85% of the maximum outer diameter, and wherein an outer diameter of the occlusion element increases along the longitudinal axis to the maximum outer diameter.

Systems and methods for treating aneurysms

An apparatus for treating an aneurysm in a blood vessel includes an occlusion element including a first tubular mesh having a first end and a second end coupled together at a proximal end of the occlusion element such that an intermediate portion of the first tubular mesh between the first end and the second end includes a substantially 180 degree turn, the intermediate portion of the first tubular mesh extending distally from the proximal end of the occlusion element, wherein the intermediate portion of the first tubular mesh has a collapsed configuration and is configured to expand to an expanded. In some embodiments, the apparatus further includes a second tubular mesh having a first end and a second end coupled to the proximal end of the occlusion element such that an intermediate portion of the second tubular mesh between the first end and the second end includes a substantially 180 degree turn. In some embodiments, the apparatus further comprises a cover coupled to the proximal end of the occlusion element.

Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a pre-determined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device.

Skin treatment devices

A vaso-occlusive system configured for embolizing an aneurysm, includes an implantable vaso-occlusive device coupled to a distal end of an elongate pusher and having a collapsed delivery configuration and an expanded, deployed configuration, wherein the vaso-occlusive device includes a proximal end configured to seat against the aneurysm adjacent the neck of the aneurysm, a distal end configured to extend in the sac and away from the neck of the aneurysm, and a central longitudinal axis, and wherein the vaso-occlusive device is configured to be releasably coupled to the distal end of the pusher at a releasable joint including either one or both of the configurations in the list consisting of: (1) the distal end of the pusher extends from the releasable joint at an angle formed with the central longitudinal axis of between about 30 degrees and about 120 degrees, and (2) the releasable joint is coupled at a location on the proximal end of the vaso-occlusive device that is radially offset from the central longitudinal axis.

In embodiments of an obstruction removal device, system, and/or method, a removal tool is disposed at a distal end of a delivery tool and configured to at least partially separate an obstruction from an inner surface of a vasculature. An expandable member is also coupled to the delivery tool. The expandable member includes a proximal end that is free or slidably coupled to the delivery tool. The proximal end of the expandable member is configured to invert or slide toward a distal end of the expandable member, thereby causing the expandable member to surround at least a portion of the obstruction and the removal tool so that the obstruction is captured between the expandable member and the removal tool, when the delivery tool is withdrawn from the vasculature to remove the removal tool and the obstruction from the vasculature.

Apparatus, system, and method for vasculature obstruction removal

An obstruction removal device is configured to be inserted through a catheter and at least partially extended into a vasculature from a distal end of the catheter. The obstruction removal device includes: a base member configured to engage one or more guide stops at the distal end of the catheter; a tubular member coupled to the base member and configured to apply a suction force from the catheter to an obstruction to remove the obstruction from the vasculature; and an expandable member surrounding the tubular member. The expandable member is configured to transition from a contracted state to an expanded state after the expandable member is at least partially extended into the vasculature from the distal end of the catheter. The expandable member is further configured to at least partially surround the obstruction as the obstruction is being removed from the vasculature.

In embodiments of an obstruction removal device, system, and/or method, an expandable member is configured to be slidably coupled to a guide wire. The expandable member is configured to surround at least a portion of an obstruction captured by a stentriever as the expandable member transitions from the expanded state to the contracted state, i.e., when the guide wire is removed from a vasculature to remove the stentriever and the obstruction from the vasculature. A first locking member is located at a base of the expandable member. The first locking member is configured to engage a second locking member that is located on the guide wire, the stentriever, or an inner surface of a guide catheter, thereby coupling the expandable member to the guide wire, the stentriever, or the inner surface of the guide catheter when the expandable member is deployed within the vasculature.

In embodiments of an obstruction removal device, system, and/or method, a removal tool and an expandable member are configured to be disposed at a distal end of a delivery tool. The removal tool may include peeler wires and hook wires that are configured to at least partially separate an obstruction from an inner surface of a vasculature. The expandable member is configured to at least partially surround the removal tool and is further configured to grasp at least one portion of the removal tool and the obstruction as the expandable member transitions from an expanded state to a contracted state when the delivery tool is removed from the vasculature to remove the removal tool and the obstruction from the vasculature.

An apparatus for treating an aneurysm includes an occlusion element configured to be releasably coupled to an elongate delivery shaft and including an inverted mesh tube having an outer layer and an inner layer, the outer layer transitioning to the inner layer at an inversion fold, the occlusion element configured to be delivered in a collapsed configuration through an inner lumen of a delivery catheter and further configured to expand to an expanded configuration when advanced out of the delivery catheter, wherein in the expanded configuration, at least the outer layer of the inverted mesh tube is formed into an expanded shape including a proximal section having a first transverse dimension, a distal section having a second transverse dimension, and a waist portion having a third transverse dimension, wherein the third transverse dimension is less than the first transverse dimension, and the third transverse dimension is less than the second transverse dimension, and wherein in the expanded configuration, the waist portion is configured to be deformed by an externally applied force such that a distance between the distal section and the proximal section is decreased.

Growing community of inventors

Santa Clara, CA, United States of America

Brett Allen Follmer