Mayo Foundation for Medical Education and Research

University of Illinois

International Clinical Research Center at St. Anne's University Hospital in Brno

Brent M Berry

Gregory A Worrell

Vaclav Kremen

Gary C Sieck

Erik S Daniel

Squire Matthew Stead

Ravishankar Krishnan Iyer

Benjamin H Brinkmann

Soudabeh Kargar

Jan Cimbalnik

Carlos B Mantilla

Obaid Khurram

Benjamin I Brinkmann

Joseph D Mozingo

Yogatheesan Varatharajah

Michal T Kucewicz

Zbigniew Kalbarczyk

Squire Matt Stead

Zbignlew Kalbarczyk

Ravishankar Krishman Iyer

This specification discloses systems, methods, devices, and other techniques for determining the location of a seizure-generating region of the brain of a mammal.

Seizure onset zone localization

A behavioral state of a brain is classified by automatically selecting one or more sensors based on the signals received from each sensor and one or more selection criteria using one or more processors, calculating at least one measured value from the signal(s) of the selected sensor(s), classifying the behavioral state as: (a) an awake state whenever the measured value(s) for the selected sensor(s) is lower than a first threshold value, (b) a sleep state (N2) whenever the measured value(s) for the selected sensor(s) is equal to or greater than the first threshold value and the measured value(s) is not greater than a second threshold value, or (c) a slow wave sleep state (N3) whenever the measured value(s) from the selected sensor(s) is greater than the first threshold value and the measured value(s) is greater than the second threshold value, and providing a notification of the classified behavioral state.

System and method for classifying and modulating brain behavioral states

This document describes methods and devices for using electrical stimulation to control physiological functions such as breathing of patients suffering from respiratory impairment. For example, this document describes methods and devices for generating effective breaths and airway protection by determining times and depths of breaths in accordance with physiological demand, and coordinating respiratory muscle stimulation with the breaths to control breathing.

Systems and methods for controlling breathing

Growing community of inventors

Rochester, MN, United States of America

Brent M Berry