Griffin Analytical Technologies, L.l.c.

Flir Detection, Inc.

Brent Knecht

Garth E Patterson

Gary Gentry

Mass spectrometry instruments are provided that are configured to provide dynamic switching between positive and negative ion preparation and analysis during a single sample analysis. Mass spectrometry analysis methods are also provided that can include switching between positive and negative ion preparation and analysis during a single sample analysis.

Mass analysis instruments and methods

The present invention relates to a mass spectrometer, and more specifically a portable mass spectrometer. In one implementation, the mass spectrometer includes a toroidal transformer. In another implementation, the mass spectrometer includes feedback circuitry to monitor signals applied in the mass spectrometer.

Portable mass spectrometers

The present invention provides methods and electronic circuits for a chemical analyzer, for example, a mass spectrometer, which provide generated signals that are maintained to a required level of precision. A user may specify the required precision for the signals which operate the spectrometer and may specify the required precision for the mass analysis, either explicitly or by choosing a predefined configuration. The spectrometer will then generate the signals to the required precision despite changes in operating conditions, environmental conditions, component aging and degradation, or other nonfailure effects that otherwise affect analyzer calibration and signal output. The electronic circuits incorporate signal monitoring to maintain closed-loop signal control. The closed-loop control includes a feedback path which may include discrete components and may include software enabling a processor to adjust the generated signals to maintain the required precision of the signals and analysis. Further, the spectrometer may monitor signals and analyze and store data in order to predict future performance, including precision, analysis limitations, impending component degradation or failure, or another parameter associated with a component or signal of the spectrometer. Specifically, a range for a particular parameter may be specified and a indication provided to a user when the parameter exceeds the specified range.

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Lebanon, IN, United States of America

Brent Knecht