The University of Toledo

Brent D Cameron

Dong-Shik Kim

Brandon W Clarke

Anthony J Webb

Scott M Pappada

Byung-Wook Park

Rui Zheng

Sensors for target entities having functionalized thereon, at least one aptamer specific to the target entity, and methods of making and using the same are described for use in glycated protein monitoring and/or biomarkers.

Methods and devices for detection and measurement of analytes

Described herein is an integrated Faraday modulator and Faraday compensator (IFMC) system. Further described are methods of making an IFMC system, methods of customizing an IFMC system for a specific application, and methods of optimizing an IFMC system for a specific application. Further described is a robust 3D Finite Element Model (FEM) for designing and optimizing an IFMC system. Further described are optical instruments comprising an integrated Faraday modulator and Faraday compensator requiring only one optical crystal.

Integrated magneto-optic modulator/compensator system, methods of making, and methods of using the same

Sensors for target entities having functionalized thereon, at least one amine-terminated aptamer specific to the target entity, and methods of making and using the same are described.

Amine-terminated aptamer functionalized surface plasmon resonanace sensors, methods of making and methods of using same

Aptamers for detection and measurement of analytes

A noninvasive method and apparatus for determining analyte concentration (e.g., glucose) in a subject that includes measuring light refraction from at least a portion one or more structures. One example of such structure is the subject's iris.

Non-invasive ocular analyte sensing system

A multifunctional neural network system for prediction which includes memory components to store previous values of data within a network. The memory components provide the system with the ability to learn relationships/patterns existent in the data over time.

Neural network system and uses thereof

Neural network for glucose therapy recommendation

A noninvasive polarimetric apparatus used to measure levels of a substance in a sample in the presence of dynamically changing sample birefringence is provided. A polarization system generates multiple states of polarized light which interact with the sample. An analyzer system receives a signal from the sample and generates a secondary signal. This signal is detected and then processed to measure levels of a substance in a sample that may be have time varying birefringent components.

Non-invasive polarimetric apparatus and method for analyte sensing in birefringent media

The present invention relates to a system and method for compensating for the effects of birefringence in a given sample and employs an optical birefringence analyzer to sense the real-time birefringence contributions and then provides a feedback signal to a compound electro-optical system that negates the birefringence contributions found in the given sample. The birefringence contribution vanishes, thus significantly reducing the main error component for polarimetric measurements.

Growing community of inventors

Waterville, OH, United States of America

Brent D Cameron