Allergan Pharmaceuticals International Limited

Warner Chilcott Company, LLC

Allergan Therapeutics LLC

Brendan Muldoon

Ryan Gerald Loughlin

Gerarde Sweeney

Emma Karen Boyd

Claire Gilligan

Colin Lorimer

A pharmaceutical soft gelatin capsule dosage form that includes (a) a shell that includes gelatin; and (b) a fill that includes at least one active ingredient, one or more polyethylene glycol, and a modified guar gum. The pharmaceutical soft gelatin capsule dosage form maintains its shell integrity (hardness) and fill viscosity after storage.

Pharmaceutical soft gelatin capsule dosage form with modified guar gum

The present invention relates to a process for the preparation of an intravaginal matrix drug delivery device. The process comprises the steps of combining at least one therapeutic agent in a therapeutically effective amount with at least one biocompatible elastomeric polymer to form a mix; curing said mix in a mold having a shape of said intravaginal drug delivery device, to form a polymer matrix; and maturing said polymer matrix to form the intravaginal drug delivery device. The maturing step alters the release rate characteristics of a device prepared in accordance with the process of the invention.

Intravaginal matrix drug delivery devices

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Newtownabbey, Ireland

Brendan Muldoon