Berkeley Lights, Inc.

Phenomex Inc.

Brandon R Bruhn

Eric D Hobbs

Troy A Lionberger

Keith J Breinlinger

J Tanner Nevill

Andrew W McFarland

John A Tenney

Volker L S Kurz

Xiaohua Wang

Paul M Lebel

Kai W Szeto

Eric Sackmann

Kellen C Mobilia

Darshan Thaker

Matthew E Fowler

Eric K Sackmann

Samira A Nedungadi

Nenad Bozinovic

Daniel A Banda Villanueva

Andrew W Mcfarland

Volker Ls Kurz

Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.

Microfluidic devices for optically-driven convection and displacement, kits and methods thereof

A system and a method for dynamically optimizing an instrument system workflow based on operational monitoring and managing of a workflow for a hardware system. The system includes instrument resources and sample chambers, each resource and chamber with a dedicated sensor configured to acquire data. The system further includes a computing device communicatively connected to the instrument resources and sample chambers. The computing device includes a software application or program comprising a workflow builder, an execution engine, an analytics engine, a virtual system modeling engine, and an optional machine learning engine.

Systems and methods for optimizing an instrument system workflow

Optically-actuated microfluidic devices permit the use of spatially-modulated light to manipulate micro-objects such as biological cells. Systems and methods are described for providing sequences of light patterns to move and direct a plurality of micro-objects within the environment of a microfluidic device. The sequenced light patterns provide improved efficiency in directing the transport of the plurality of micro-objects. Other embodiments are described.

Light sequencing and patterns for dielectrophoretic transport

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San Francisco, CA, United States of America

Brandon R Bruhn