Depuy Synthes Products, Inc.

Other

Synthes USA, LLC

Synthes Gmbh

Brandon L Randall

Dominique D Messerli

Ryan T Walsh

Peter Fatone

Lawton Laurence

Sean Hamilton Kerr

Thomas Kueenzi

Thomas Pepe

Ali Cem Recber

Jacqueline Myer

Markus Hunziker

David K Koch

David Edgar Evans

Christopher M Angelucci

Michael L Boyer

Robert J Delurio

Shuguang Li

Michael L Boyer, Ii

Roger D Goodwin

Raveendra Pottathil

Michael L Ii Boyer

A method of forming an access opening through a psoas muscle to a patient's spine includes laterally inserting a stimulating dilator into the psoas muscle. The stimulating dilator has a stimulation channel formed in an outer surface thereof. An electrical pulse is transmitted into the stimulating dilator to locate a position of a nerve in the patient's psoas muscle. The stimulating dilator is laterally inserted through the psoas muscle and toward the patient's spine in a way that avoids the nerve. A stimulating probe is inserted into the stimulation channel along the outer surface of the stimulating dilator while transmitting an electrical pulse into the stimulating probe to verify the position of the nerve.

Dilation system and method of using the same

An intervertebral spacer implant () is provided with a retention mechanism () to help alleviate expulsion and movement of the implant when placed in the spine while providing an implant that is easier to insert in the spine. In one embodiment the retention mechanism comprises a keel on at least one of the inferior or superior faces of the spacer implant preferably extending in an anterior-posterior direction. In another embodiment the implant comprises a spacer () and a plate (), the plate comprising a supplemental or alternative retention mechanism. In one embodiment the retention mechanism comprises one or more holes () in the anterior end of the plate. In yet another embodiment, the retention mechanism comprises one or more blades that are in a first position when inserted and are preferably rotated to a second position that engages the superior and inferior vertebrae.

Intervertebral implant with fixation geometry

Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants.

Porous biocompatible polymer material and methods

A method of forming an access opening through a psoas muscle to a patient's spine includes laterally inserting a stimulating dilator into the psoas muscle. The stimulating dilator has a stimulation channel formed in an outer surface thereof. An electrical pulse is transmitted via an EMG into the stimulating dilator to locate a position of a nerve in the patient's psoas muscle. The stimulating dilator is laterally inserted through the psoas muscle and toward the patient's spine in a way that avoids the nerve. A stimulating probe is inserted into the stimulation channel along the outer surface of the stimulating dilator while transmitting an electrical pulse via the EMG into the stimulating probe to verify the position of the nerve.

Directional sequential and blunt stimulating dilation systems () and related methods for accessing a patient's spine () though the patient's psoas muscle () include sequential directional dilators () or a blunt stimulating dilator (') with at least one channel formed therein. Neural elements or nerves () of the psoas muscle are preferably mapped using a stimulating probe (). The stimulating probe is inserted through the psoas muscle toward the patient's spine. The directional sequential dilators may be inserted to dilate the tissue on any side of the stimulating probe without significantly impacting tissue on the opposite side of the stimulating probe, which may be located, proximate the neural elements. The dilators are rendered directional by having bores (), by means of which they can be inserted over each other and over the probe, which are offset from their longitudinal axes ().

Embodiments described include devices and methods for forming a porous polymer material. Devices disclosed and formed using the methods described include a spacer for spinal fusion, craniomaxillofacial (CMF) structures, and other structures for tissue implants.

An allogenic implant for use in intervertebral fusion is formed from one or more two pieces. The pieces are made from bone, and are joined together to form an implant having sufficient strength and stability to maintain a desired distance between first and second vertebrae in a spinal fusion procedure. The implant pieces may be formed of cortical bone and connected by dovetail joints, and at least one cortical bone pin may be provided to lock the pieces together and to add strength to the implant. Teeth are formed on the vertebra engaging surfaces of the implant prevent short-term slippage of the implant.

Allograft implant

Optical bio-discs for biochemical analysis, bio-disc analysis systems and biochemical analysis methods are described herein. In one embodiment, the bio-disc includes a sample analysis circuit that includes a separation membrane for separating an investigational feature of a sample. The bio-disc also includes a conjugate release pad, and an analysis membrane containing analysis zones that may be analyzed for the presence of analytes. An analysis method includes providing a sample to a separation membrane in a bio-disc, separating an investigational feature from the sample using a separation membrane, mixing reagents that include signal elements for detecting an analyte with the investigational feature so as to form a reagent-investigational feature mixture and capturing an analyte with a signal element bound thereto in an analysis zone on an analysis membrane. The method further includes determining the presence of an analyte by analyzing the signal elements present in the capture zone of the analysis membrane.

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West Chester, PA, United States of America

Brandon L Randall