Mayo Foundation for Medical Education and Research

Boston Scientific Scimed, Inc.

Brandon J Tefft

Gurpreet S Sandhu

Daniel B Spoon

Patrick A Haverkost

Timothy A Ostroot

Roger W McGowan

Dan Dragomir-Daescu

Alexander J Wiedmann

Susheil Uthamaraj

Jennifer Reinhart

This document provides devices and methods for the treatment of heart conditions such as valvular stenosis. For example, this document provides devices and methods by which a guide catheter can align itself with a blood flow stream to thereby help direct a guidewire or other elongate device transmitted from the guide catheter through an orifice of a heart valve.

Device and methods for self-centering a guide catheter

In some aspects, the present disclosure pertains to self-expanding emboli-capturing centering devices for centering a medical instrument in a conduit within a patient. The centering devices comprise (a) an elongate shaft, (b) a self-expanding centering member having an open distal end and an inner surface forming a central lumen with a flared distal portion, the centering member being configured such that a fluid flowing in a distal-to-proximal direction that is received by the open distal end flows proximally along the flared distal portion of the central lumen before exiting the central lumen through one or more openings in a proximal portion of the centering member, and (c) a filter material configured to filter the fluid received by the open distal end of the centering member. Other aspects of the present disclosure pertain to systems and methods employing such centering devices.

Emboli-capturing centering device

Magnetic vascular grafts and methods for their use are provided herein.

Devices and methods for endothelialization of magnetic vascular grafts

Growing community of inventors

Rochester, MN, United States of America

Brandon J Tefft