Baxter International Inc.

Life Technologies Corporation

Hynetics LLC

Hyclone Laboratories, Inc.

Nestec S.a.

Baxter Healthcare Sa

Float Machines Inc.

Bradley H Buchanan

Michael E Goodwin

Nephi D Jones

Sidney T Smith

Larry A Rosenbaum

Arnold C Bilstad

Gregory P Elgan

Steven H Giovanetto

Jim A Austin

Kenneth Bibbo

Gregg Nebgen

David V Bacehowski

T Michael Dennehey

Archie Woodworth

Alan W Martilla

Claudio Branch

Suchuan C Fan

Y Samuel Ding

Jeremy K Larsen

Balakrishna Reddy

Whitt F Woods

William S Hurst

Gene Frank Clyde

Alan W Marttila

J Antonio Gutierrez

Adel M Sadik

M Jeffrey Willey

William S Hoerle

Annette M Nikolis

Chee Kok Ong

Melissa J Skelnik

William Wages

Francis J Otto, Jr

A method for collecting a sterilized fluid includes passing a fluid through an inlet stem and into a chamber of a storage container so that the fluid collects within the chamber of the storage container; and applying a beam of radiation to the inlet stem so that the beam of radiation passes through the inlet stem and through at least a portion of the fluid passing through the inlet stem, the beam of radiation at least partially sterilizing the fluid passing through the inlet stem and into the chamber of the storage container.

Containers and systems for processing a fluid

A container includes a first wall and an opposing second wall that extend between a first end and an opposing second end, a first fluid flow path being bounded between the first wall and the second wall. An inlet is formed at the first end and communicates with the first fluid flow path. An outlet is formed at the second end and communicates with the first fluid flow path. The first wall includes a primary wall portion having a first opening extending therethrough in alignment with the first fluid flow path. A secondary wall portion extends over the first opening and is secured to the primary wall portion so as to seal the first opening closed, the secondary wall portion being comprised of a film having a thickness that is less than a thickness of the primary wall portion.

A container includes a first wall made of a polymeric material, a second wall made of a polymeric material, and a plurality of elongated baffles, spacers or seam lines formed between the first wall and the second wall to form a plurality of separate fluid flow paths. Each of the plurality of fluid flow paths are separated from the other fluid flow paths by at least one of the baffles, spacers or seam lines. Each of the plurality of fluid flow paths have a first end in fluid communication with an inlet and have a second end in fluid communication with an outlet.

A system for sterilizing a fluid includes a sterilization container bounding a fluid flow path that can be coupled with a fluid source. The sterilization container is comprised of one or more polymeric walls. A beam generator is configured to direct a beam of electromagnetic radiation through at least a portion of the fluid flow path of the sterilization container, the beam of electromagnetic radiation being sufficient to sterilize a fluid within the fluid flow path.

Systems and containers for sterilzing a fluid

A system for sterilizing a fluid includes a fluid source and a sterilization container bounding a fluid flow path that is in fluid communication with the fluid source. The sterilization container is comprised of one or more polymeric walls. An electron beam generator is configured to direct an electron beam through at least a portion of the fluid flow path of the sterilization container, the electron beam being sufficient to sterilize a fluid within the fluid flow path.

Systems and containers for sterilizing a fluid

A system for forming a fluid connection includes a first connector and a second connector. Both connectors include a tubular body having a membrane mounted on a distal end thereof. A support member facilitates the coupling of the connectors together so that the membranes are abutted together. Radiant energy is applied to the abutted membranes so as to first sterilize the membranes and then melt the membranes so that a passage is formed therethrough.

Sterile connector systems

The connection, assembly, or fill of two or more pre-sterilized components having at least one terminal end each for attachment to another component, and an apparatus for performing such a connection, while maintaining the sterility of the components is disclosed. The resulting connection is made permanent by bonding the contacting components together using either a solvent bonding technique, a radio frequency sealer, a heat sealer, or any other suitable process. The connection is preferably made within an active sterile field. Using a low-voltage electron beam instrument, such as the MIN-EB&#x2122;, a suitable sterile field sphere can be created. The terminal ends of the multiple components remain within the sterile field sphere until the possibility of contamination within the sealed components is significantly reduced to industry acceptable standards.

Method and apparatus for manipulating pre-sterilized components in an active sterile field

A feed bag includes a body bounding a compartment, the compartment being adapted to hold a feed material. The body has a first end with an outlet formed thereat and an opposing second end. A vent port is formed on the body so as to communicate with the compartment. In one embodiment a filter is coupled with the vent port. A fluid port is formed on the body so as to communicate with the compartment. The fluid port is adapted to receive a fluid line for delivering a fluid into the compartment of the body.

Feed bags and methods of use

The invention relates to a method for sealing a peripheral attachment member onto a sealed pouch that has been previously filled with a product. The invention also relates to a pouch that includes a peripheral attachment member sealingly attached to at least one of its faces. The method includes a step of providing a multi-layer pouch that is configured so as to provide an inner sealant adapted to form a closed enclosure along sealing lines and an outer sealant that forms at least one external face of the pouch wherein the outer sealant has a melting point that is lower than the melting point of the inner sealant.

Method for sealingly attaching a peripheral attachment member onto a filled-sealed pouch

A method for mixing a solution includes positioning a collapsible container within a chamber of a substantially rigid tank. The collapsible container bounds a compartment. A mixer is disposed within the compartment of the container. Two or more components are fed into the compartment of the container. At least one of the components is a liquid. The mixer is raised and lowered within the compartment of the container so as to mix the components.

Methods for mixing solutions

The present invention provides a receptacle for a therapeutic fluid susceptible to deterioration on exposure to a gas such as oxygen or carbon dioxide. The receptacle has walls of sheet material each including at least one layer forming a barrier essentially impermeable to such gas, and a seal sealing the walls together in a region thereof. A transfer tube is sealed in the seal having a proximal end in the receptacle, a distal end accessible from outside the receptacle, a flow passage extending between said proximal and distal ends, and a closure blocking flow through the flow passage adapted to be pierced by a tubular needle for transfer of therapeutic through the needle. The transfer tube and closure are essentially impermeable to said gas.

High gas barrier receptacle and closure assembly

A mixing tank assembly includes a side wall having an interior surface at least partially bounding a chamber. A floor is disposed within or at the base of the chamber. The floor can be either fixed to the side wall or movably disposed within the chamber thereof. A collapsible container is disposed within the chamber so as to rest on the floor. The collapsible container bounds a compartment. A mixer is disposed within the compartment of the container.

Mixing tank assembly

A mixing system includes a flexible mixing bag having an interior surface bounding a compartment, the compartment being adapted to hold a liquid solution. A mixer is disposed within the compartment of the mixing bag. A shaft has a first end and an opposing second end. The first end of the shaft is connected to the mixer within the compartment of the mixing bag. The second end of the shaft is disposed outside of the compartment. A seal is formed between the mixing bag and the shaft or the mixer to enable the shaft to raise and lower the mixer within the compartment of the mixing bag while preventing leaking of the liquid solution.

Growing community of inventors

Lopez Island, WA, United States of America

Bradley H Buchanan