Alza Corporation

Incline Therapeutics, Inc.

Ethicon Endo-surgery, Inc.

Ethicon, Gmbh

Bradley E White

John Timothy Lemke

Brian W Read

Corinna X Chen

Andrew T Beckman

Jason E Dougherty

Cory G Kimball

Christopher J Schall

Jason L Harris

Jeffrey S Swayze

Prasanna Malaviya

Paul B Guerra

Frederick E Shelton, IV

Foster B Stulen

Jeffrey L Aldridge

Gary Lee Long

Gregory W Johnson

Thomas W Huitema

Matthew C Miller

Timothy G Dietz

James R Giordano

David A Witt

Michael S Cropper

Tamara S Widenhouse

Sean P Conlon

Craig N Faller

David Keith Norvell

Zhifan F Huang

Patrick A Weizman

Paul G Hayter

John F Cummings

Al Mirel

Mary E Mootoo

Jane A Sheetz

Paul G Ritchie

Raymond M Banks

David R Seward

Zita S Netzel

David C Youmans

Scot Satre

Randal T Byrum

Robert J Dunki-Jacobs

Robert Mason Trusty

Kurt R Bally

Jere J Brophy

Steve G Bernath

Frederick E Iv Shelton

John Lemke

Paul Hayter

Gregory M Johnson

Devices, systems and methods for controlling the application of current and/or voltage to deliver drug from patient contacts of an electrotransport drug delivery device by indirectly controlling and/or monitoring the applied current without directly measuring from the cathode of the patient terminal. In particular, described herein are electrotransport drug delivery systems including constant current delivery systems having a feedback current and/or voltage control module that is isolated from the patient contacts (e.g., anodes and cathodes). The feedback module may be isolated by a transistor from the patient contacts; feedback current and/or voltage control measurements may be performed at the transistor rather than at the patient contact (e.g., cathode).

Current control for electrotransport drug delivery

In various embodiments, a surgical instrument is provided that may comprise an end effector for performing a surgical procedure on tissue, for example. The end effector may comprise at least one energy delivery surface and heat dissipation means for dissipating heat from at least a portion of the end effector. For example, in at least one embodiment, the end effector may comprise a first jaw, a second jaw, and a cutting member. The cutting member may comprise a cutting surface and a body, which may define a cavity and at least one opening communicating with the cavity. A fluid may be moved through the cavity to and/or from the opening(s). Additionally, in at least one embodiment, a surgical instrument's end effector may comprise a first jaw, a second jaw, a cutting member, and at least one heat pipe. Various other heat dissipation means are also disclosed.

Heat management configurations for controlling heat dissipation from electrosurgical instruments

Electrotransport drug delivery devices, system and methods of using configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices/systems may include an off-current module to determine that any current (e.g., which may be inferred by measuring potential difference between the anode and cathode of the device) flowing between the anode and cathode is below a threshold value when the device is not supposed to be delivering drug, thereby preventing unintended delivery of drug and/or alerting a user that unintended delivery of drug may occur.

Self-test for analgesic product

A switch operated therapeutic agent delivery device is described. The device comprises two parts, which are assembled by a user prior to use. A first part contains a power supply and circuitry for the device; and a second part comprises electrodes and reservoirs containing the therapeutic agent to be delivered. The action of combining the two parts of the device causes the two parts to be irreversibly coupled together, completes an electrical connection between the two parts, and closes one or more switches, thereby connecting a power source, such as a battery, into the device's circuitry, thereby powering the device on so that it is ready for use. The device can then be attached to a patient, who can operate the device by pressing a button in a proper sequence.

Method of storing an electrotransport drug delivery device

A module for attachment to a medical instrument to scan the anatomy with a beam of radiation. The module comprising a housing suitable for insertion in the anatomy that includes a window and a fastener to attach the housing to a medical instrument, an oscillating reflector within the housing that directs a beam of radiation onto the anatomy, and a collector to receive radiation returned from the anatomy.

Optical scanning module and means for attaching the module to medical instruments for introducing the module into the anatomy

A surgical instrument for supplying energy to tissue can comprise a jaw member comprising an electrode, wherein the electrode is configured to supply energy from a power source to captured tissue. The surgical instrument comprises a tissue-cutting element to transect the captured tissue. The rate of distal translation of the tissue-cutting element during the operational stroke may be regulated by an electromagnetic brake.

Electrosurgical cutting and sealing instrument

An electrosurgical surgical instrument can comprise a handle and an end effector, wherein the end effector can comprise first and second jaws which can be opened and closed to capture tissue therebetween. One or both of the first and second jaws can comprise a plurality of electrodes which can be sequentially activated. The electrodes can be activated in a predetermined order in connection with a cutting member being advanced through the tissue. In various embodiments, the electrodes can be deactivated in a predetermined order. In certain embodiments, the electrodes can be comprised of a positive temperature coefficient material which can allow the electrodes to be sequentially deactivated.

Electrosurgical instrument comprising sequentially activated electrodes

A surgical stapling assembly is configured to be used to form a tissue seal having an arcuate portion. The surgical stapling assembly comprises an end-effector extending from the distal end of the shaft. The end-effector comprises a first portion and a second portion. The first portion comprises a first face at least partially surrounding the aperture, a staple cavity defined in the first face, a staple removably positioned within the staple cavity, and a first electrode positioned one of on and proximate to the first face. The second portion comprises a second face, an anvil pocket defined in the second face, and a second electrode positioned one of on and proximate to the second face, and a second electrode. The first electrode and the second electrode each comprise an arcuate portion. The first electrode has a different polarity than the second electrode.

Surgical instruments with electrodes

Two-part electrotransport device

A method for viewing a portion of a patient's anatomy that comprises placing a scanner assembly including an oscillating reflector in the anatomy, securing the scanner assembly to an anatomical structure, scanning the anatomy with the scanner assembly secured to the anatomical structure, collecting radiation returned from the scanned anatomy, and generating a displayable image of the anatomy.

Methods for imaging the anatomy with an anatomically secured scanner assembly

Growing community of inventors

Cincinnati, OH, United States of America

Bradley E White