Syn X Pharma, Inc.

Artemis Proteomics, Ltd.

Nanogen, Inc.

Nexus Dx, Inc.

Brad Thatcher

George Jackowski

Jason Yantha

John G Marshall

Tammy Vrees

Rulin Zhang

Tracy Van Lieshout

Michele Rasamoelisolo

The invention provides an assay for the quantification of circulating glycophorin in biological fluid samples. The circulating glycophorin measured by this assay is a truncated glycophorin diagnostic for congestive heart failure (CHF).

Diagnostic methods for congestive heart failure

The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of at least one disease state relative to recognition of the presence and/or the absence of the biopolymer.

Biopolymer marker indicative of disease state having a molecular weight of 1562 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1348 daltons

The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of at least one disease state relative to recognition of the presence and/or the absence of a biopolymer.

Biopolymer marker indicative of disease state having a molecular weight of 1525 Daltons

Method and kit for diagnosing myocardial infarction

Biopolymer marker indicative of disease state having a molecular weight of 2753 daltons

The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least one particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of said at least one disease state relative to recognition of the presence and/or the absence of said biopolymer.

Biopolymer marker indicative of disease state having a molecular weight of 1211 daltons

The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopolymers verified within such a sample is then viewed with reference to their ability to evidence at least particular disease state; thereby enabling a diagnostician to gain the ability to characterize either the presence or absence of at least one disease state relative to recognition of the presence and/or the absence of the biopolymer.

Biopolymer marker indicative of disease state having a molecular weight of 1077 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1793 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1350 daltons

Biopolymer marker indicative of disease state having a molecular weight of 2021 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1521 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1097 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1206 daltons

Biopolymer marker indicative of disease state having a molecular weight of 1465 daltons

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Toronto, Canada

Brad Thatcher