Pioneer Hi-bred International, Inc.

E.i. Dupont De Nemours and Company

Poineer Hi-bred International, Inc.

Corteva Agriscience LLC

Brad Poland

Andre R Abad

Jimei Wang

Lu Liu

Thomas Chad Wolfe

Genhai Zhu

Weiping Xie

Lan Zhou

Ute Schellenberger

Xiaomei Shi

Zhenglin Hou

Jun-Zhi Wei

Ingrid Udranszky

Andrew Carl Crow

Hua Dong

Eric J Schepers

Nasser Yalpani

Sue B Lo

Jennifer Kara Barry

James J English

Kevin Hayes

Amy Lum

Christian Tor Bartholomay

Jarred Kenneth Oral

Louisa D'Lima

Kevin Robert Hayes

Eric Jude Schepers

The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding polypeptides having pesticidal activity against insect pests, including Lepidopteran and Coleopteran. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

Insecticidal polypeptides and uses thereof

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.

Insecticidal proteins and methods for their use

The disclosure provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the disclosure provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

Broad spectrum insecticidal polypeptide against lepidopteran pests and methods of use thereof

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity. Structure based methods for engineering insecticidal proteins of the disclosure to have modified physical properties are provided.

Structure based methods for modification of PIP-72 polypeptides and PIP-72 polypeptides derived therefrom

The invention provides nucleic acids, and variants and fragments thereof, obtained from strains ofencoding polypeptides having pesticidal activity against insect pests, including Lepidoptera and Coleoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

Insecticidal polypeptides having broad spectrum activity and uses thereof

Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are isolated insecticidal proteins and nucleic acids. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.

Insecticidal proteins and methods of use

Growing community of inventors

Monroe, IA, United States of America

Brad Poland