Specgx LLC

Mallinckrodt, Inc.

Brad L Gower

Jae Han Park

Clifford J Herman

Carlos H Castaneda

Tsz Chung Lai

Kai Feng

Pharmaceutical compositions comprising at least one active pharmaceutical ingredient or a pharmaceutically acceptable salt thereof, at least one hydrophilic plastomer, at least one hydrophilic elastomer, and at least one deliquescent plasticizer, wherein the pharmaceutical compositions provide extended release of the API and have abuse deterrent properties. Methods for preparing the pharmaceutical compositions in which the components of the composition are humidified such that the deliquescent plasticizer deliquesces, thereby plasticizing the hydrophilic polymers.

Extended release, abuse deterrent pharmaceutical compositions

A pharmaceutical composition comprising at least one active pharmaceutical ingredient (API) or a pharmaceutically acceptable salt thereof, a glucomannan, a first polyalkylene oxide having an average molecular weight of no more than 300,000, and a second polyalkylene oxide having an average molecular weight of at least 1,000,000 and methods of making. The pharmaceutical composition provides extended release of the API and has abuse deterrent features.

Glucomannan containing pharmaceutical compositions with extended release and abuse deterrent properties

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O'Fallon, IL, United States of America

Brad L Gower