Battelle Memorial Institute

Boyu Yang

Esley M Heizer

Brian A Young

Daniel M Bornman

Mark E Hester

Angela T Minard-Smith

William Eugene Dunbar Godbold

In one illustrative embodiment, an allelotyping method may include selecting a plurality of text strings that each represent a nucleotide sequence that was read by a massively parallel sequencing (MPS) instrument, where the nucleotide sequences represented by the selected plurality of text strings each correspond to a particular locus, comparing the selected plurality of text strings to one another to determine an abundance count for each unique text string included in the selected plurality of text strings, and determining one or more alleles for the particular locus by comparing the abundance count for each unique text string included in the selected plurality of text strings to an abundance threshold.

Allelotyping methods for massively parallel sequencing

Illustrative embodiments of custom knowledgebases and sequence datasets, as well as related methods, are disclosed. In one illustrative embodiment, one or more computer-readable media may comprise a custom knowledgebase and an associated sequence dataset. The custom knowledgebase may comprise a plurality of assertions that have been automatically extracted from a plurality of publications, where each of the plurality of assertions encodes a relationship between a subject and an object. The sequence dataset may comprise a plurality of called biological sequences, where each of the plurality of called biological sequences is associated with one or more of the plurality of assertions of the custom knowledgebase.

Constructing custom knowledgebases and sequence datasets with publications

Growing community of inventors

Charlottesville, VA, United States of America

Boyu Yang