The General Hospital Corporation

Massachusetts Institute of Technology

Siemens Healthcare Gmbh

The Brigham and Women's Hospital, Inc.

Borjan Aleksandar Gagoski

Kawin Setsompop

Elfar Adalsteinsson

Lawrence Leroy Wald

Daniel Polak

Daniel Nicolas Splitthoff

Vijayanand Alagappan

Carolyn Mountford

Alma Gregory Sorensen

Saadallah Ramadan

Ovidiu Andronesi

Techniques are disclosed related to the compensation of phase offsets introduced into k-space lines as a result of encoding of blip gradients due when motion is present, which may be used for parallel magnetic resonance imaging (MRI) techniques such as blipped SMS or blipped CAIPIRINHA. The compensation of these additional phase offsets may prevent artifacts that would otherwise be present in the reconstructed images as a result of motion during the MRI scanning procedure. The additional phase offsets may be accounted for during the image acquisition phase of the MRI scan or, alternatively, during the image reconstruction phase.

Motion corrected blipped CAIPIRINHA and SMS

Methods for low-power in vivo localized multi-dimensional correlated magnetic resonance spectroscopy ('MRS') are provided. Low-power adiabaticity is achieved, generally, using gradient-modulated radio frequency pulses for localization and mixing. The provided pulse sequences also provide a mechanism for longitudinal mixing, which significantly increases the efficiency of magnetization transfer and thereby increases signal-to-noise ratio.

Method for two-dimensional correlation magnetic resonance spectroscopy

A method for producing a spatially and spectrally selective radiofrequency ('RF') excitation pulse includes establishing a desired spatial RF excitation pattern and establishing a desired spectral RF excitation pattern. The method also includes estimating an RF transmission profile map indicative of the transmission characteristics of an RF coil and determining, from the desired spatial and spectral excitation patterns and the estimated RF transmission profile map, at least one magnetic field gradient waveform indicative of locations in k-space to which RF energy is to be deposited. The method further includes determining, from the established spatial and spectral excitation patterns, the estimated RF transmission profile map, and the determined at least one gradient waveform, at least one RF excitation pulse waveform that will produce the desired spatial and spectral excitation patterns.

Method for producing spectral-spatial parallel RF excitation pulses for magnetic resonance imaging

Growing community of inventors

Cambridge, MA, United States of America

Borjan Aleksandar Gagoski