O2m Technologies, LLC

Other

The University of Chicago

Boris Epel

Howard J Halpern

Mrignayani Kotecha

Eliyas Siddiqui

Safa Hameed

Subramanian V Sundramoorthy

An apparatus and method for improved S/N measurements useful for electron paramagnetic resonance imaging in situ and in vivo, using high-isolation transmit/receive surface coils and temporally spaced pulses of RF energy (e.g., in some embodiments, a RF pi pulse) having an amplitude sufficient to rotate the magnetization by 180 degrees followed after varied delays, by a second RF pulse having an amplitude half that of the initial pulse to rotate the magnetization by, e.g., 90 degrees (a pi/2 pulse), to the plane orthogonal to the static field where it evolves for a short time. Then a third RF pi pulse sufficient to rotate the magnetization by, e.g., 180 degrees, forms an echo (in some embodiments, the second and third pulses are from the same signal as the first pulse but are phase shifted by 0, 90, 180, or 270 degrees to reduce signal artifact), to image human body.

Stimulated-echo imaging for EPRI

A method includes placing a sample of cells, tissue, or an organ into an oxygen imaging system, circulating a humidified gas mixture around the tissue or organ, circulating conditioned air through the oxygen imaging system to maintain a temperature around the sample, and acquiring a three-dimensional oxygen map of the sample. The oxygen map provides a quantitative measure of cell viability and functionality.

Cell viability apparatus, system, and methods thereof

A method for relaxation time determination includes delivering a series of radio frequency (RF) pulses in a sequence to a specimen having a magnetic resonance spin system. The pulses are separated by equal time intervals and the sequence has a duration comparable or greater than a spin-lattice relaxation time for the spin system. The method includes receiving a response after each RF pulse in the series. The response includes a free induction decay and spin echoes. The method includes generating a series of single point imaging (SPI) images from each response. Each SPI image of the series corresponds to an RF pulse in the series. The method includes converting SPI images to a spin-spin relaxation map and a spin-lattice relaxation map.

Pulse sequence for resonance-based tissue analysis

T-sensitive inversion-recovery imaging for EPROI

Oxygen imaging instrument

Method and apparatus for EPROI using T1e spin-lattice relaxation response

Techniques provide for passive Q switching in a bimodal resonator environment, where magnetic resonators are coupled for power transfer. A passive Q switch is responsive to a driving power from one magnetic resonator coupled to another magnetic resonator. After the driving power reaches a threshold, the passive Q switch shunts the receiving magnetic resonator, at least partially, to reduce the Q of that second resonator, which allows faster detection operation of the second resonator in some applications. The technique allows for fast Q switching in a bimodal resonator system, especially one having resonators having magnetic fields that are orthogonal to one another.

Method and apparatus for resonator signal production and measurement

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Chicago, IL, United States of America

Boris Epel