National Yang Ming Chiao Tung University

Ipreg Inc.

Ipreg Incorporation

Bor-Ran Li

Chung-Hsien Huang

Yaw-Kuen Li

Chia-Yu Chang

Chia-Jen Lee

Pei-Heng Lin

Wei-Lung Chang

Tzu-Ting Lin

Sian-Chen Sheu

Chen-Yen Chung

Ching-Wen Chang

The present invention provides a microfluidic structure for sorting targeted substances. The microfluidic structure includes: an inlet portion having at least one fluid input port; an outlet portion having a plurality of fluid output ports; a first annular flow channel communicated with the inlet portion at the upstream end and rotatably extended; and a second annular flow channel communicated with the downstream end of the first annular flow channel at the upstream end, communicated with the outlet portion at the downstream end and rotatably extended. The first annular flow channel and the second annular flow channel are connected in series according to an S-shaped track, so that the outer side wall of the first annular flow channel is continuously connected to the inner side wall of the second annular flow channel. The cross-sections of the first annular flow channel and the second annular flow channel have a height difference.

Cascaded design microfluidic structure with step difference

An impedance-type chip for real-time sensing sweat pressure, a micro-control system, and method thereof are provided for monitoring a physiological state of a subject. The impedance-type chip includes a substrate, a pair of comb-shaped electrodes, a first double-layered junction plate, a microfluidic channel plate, a second double-layered junction plate, and a sealing plate. Each the comb-shaped electrodes has a plurality of sub-electrodes and is disposed on the substrate to provide different impedance values. The first double-layered junction plate is disposed on the substrate, the microfluidic channel plate is disposed on the first double-layered junction plates, and the second double-layered junction plate is disposed on the microfluidic channel plate, wherein the first double-layered junction plate, the microfluidic channel plate, and the second double-layered junction plate have a microfluidic channel with a cavity. The sealing plate is disposed on the second double-layered junction plate to seal the microfluidic channel.

Impedance-type chip for real-time sensing sweat pressure and method thereof

The present invention provides a sperm sorting chip and a method for sorting sperm using the same. Said sperm sorting chip includes: a flow channel structure sequentially configured with a gradually diverging flow field region, a main flow channel, and a gradually converging main flow channel intercommunicated with each other from a first side end to a second side end; a fluid injection port, a semen injection port, and a semen extraction port separately located at the first side end and communicated with a main input channel of the gradual diverging flow field region; and a waste fluid outlet located at the second side end and communicated with the gradually converging main flow channel. The gradually diverging flow field region further includes a plurality of sub-input channels derived from the main input channel and converged into the main flow channel, and the plurality of sub-input channels have a gradually widening channel width at the junction with the main flow channel. By contrast, the gradually converging main flow channel has a gradually narrowing channel width toward the waste fluid outlet.

Sperm sorting chip and method for sorting sperm using the same

A biological sensing device and a method for separating a biomolecule are provided. The biological sensing device includes an amino acid sequence and a signal-generating unit. The amino acid sequence includes SEQ ID NO: 1 or SEQ ID NO: 2, and is for binding with UlaG protein labeled on a biomolecule. The signal-generating unit connects to the amino acid sequence.

Biological sensing method for separating biomolecule

Growing community of inventors

Hsinchu, Taiwan

Bor-Ran Li