Sk Chemicals Co., Ltd.

Viromed Co., Ltd.

Cmg Pharmaceutical Co., Ltd.

Pangenomics Co., Ltd.

Helixir Co., Ltd.

Bongcheol Kim

Sunyoung Kim

Chang-Kyun Han

Wie-Jong Kwak

Hyung-Jin Jung

Guang-Jin Im

Tae Kon Kim

Se Jun Yun

Mirim Jin

Soomin Lee

Wonrack Choi

Jin Sung Kim

Eun Kyung Choi

Eun-Jin Park

Jeongbeob Seo

Jung-Woo Seo

Suk Young Cho

Gilnam Lee

Hye Sun Jeon

Hwa-Jun Lee

Jin-hwan Oh

Choung Soo Kim

Jung Shin Lee

Jung Jin Hwang

Hyang Jeon

Chul Yun Rhim

Ki Joon Jeon

Chil Mann Jung

ChilMann Jung

Byung-Wook Cho

Sung-Seup Shin

Hae-Kwan Eo

Jin-Hwan Oh

Hyang Jeong

Hae Kwan Eo

The invention provides novel substituted heterocyclic compounds represented by Formula I and Formula II, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as inhibitors of MEK and are useful in the treatment of inflammatory diseases, cancer and other hyperproliferative diseases. The invention further provides a method of treatment for inflammatory diseases, cancer and other hyperproliferative diseases in mammals, especially humans.

Substituted pyridinone compounds as MEK inhibitors

The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.

Triterpene compounds which are effective on improvement of brain function

The present invention relates to a use of a crude extract, non-polar solvent soluble extract or purified extract of the hardy kiwifruit for the preparation of therapeutic agent for treating and preventing baldness disorder and seborrheic skin disease in human and mammal, and health care food, food additives, feed additives, cosmetic composition comprising the same. The hardy kiwifruit reduced blood DHT level, promoted the formation of hair root in mouse model experiment, and inhibited the falling out of hair and improved seborrheic skin disease of volunteers such as keratigenous skin, seborrhea etc.

Composition comprising an extract of hardy kiwi for preventing or treating baldness disorders or seborrheic skin disorders

This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.

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The present invention is related to pharmaceutical composition essentially comprising herbal extract of, and additionally comprising herbal extract selected from group consisting ofPericapium,according to the need for the prevention and treatment of arthritic diseases and methods of using the above extracts and composition as potent anti-inflammatory and anti-arthritic agents.

Crude drug compositions for treating or preventing arthritic diseases and the preparation process

Growing community of inventors

Gwacheon-si, South Korea

Bongcheol Kim