Samyang Biopharmaceuticals Corporation

Samyang Holdings Corporation

Samyang Corporation

Bong Oh Kim

Min Hyo Seo

Sa Won Lee

In Ja Choi

Yil Woong Yi

Hye Jeong Yoon

Joong Woong Cho

Myung Seob Shim

Do Hoon Kim

Min-Hyo Seo

Sang Jun Lee

Seong Yun Jeong

Eun Kyung Choi

Se Yoon Kim

Hye Rim Kim

Bum Chan Min

Ji Yeong Kim

Hye Won Kang

Ha Na Woo

Hye-Won Kang

Kyu Jin Kyung

A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.

Pharmaceutical composition with improved storage stability and method for preparing the same

The present invention relates to an amphiphilic block copolymer composition which provides enhanced stability to a micelle formed by an amphiphilic block copolymer in an aqueous phase.

Amphiphilic block copolymer composition having enhanced micelle stability, and pharmaceutical composition comprising same

Disclosed are microparticles containing physiologically active peptides, a method for preparing the same, and a pharmaceutical composition comprising the same.

Microparticles containing physiologically active peptide, method for preparing the same, and pharmaceutical composition comprising the same

The present invention relates to a macromolecule for delivering protein, polypeptide or peptide drugs and to a production method for the same, as well as to a slow release composition for protein, polypeptide or peptide drugs comprising the same, and more specifically relates to a polylactic acid derivative compound of Chemical formula 1 of which the numerical average molecular weight is no more than 7000 daltons and to a production method for the same, as well as to a slow release composition for protein, polypeptide or peptide drugs using the same and to a production method for the same.

Macromolecule for delivering protein, polypeptide or peptide drugs and a production method for the same, and a slow release composition for protein, polypeptide or peptide drugs and a production method for the same

Disclosed are a highly purified polylactic acid or a derivative thereof, or a salt thereof, and a method for purifying the same. The polylactic acid or a derivative thereof, or a salt thereof may be applied to various medical and drug carrier systems, or the like.

Highly purified polylactic acid or a derivative thereof, a salt of the same, and purification method thereof

The present invention relates to a polymer nanoparticle injection formulation composition containing rapamycin with improved water solubility, and more specifically, to an injection formulation composition containing rapamycin wherein water solubility is improved by solubilizing rapamycin having low water solubility with polymer nanoparticles, a preparation method thereof, and an anticancer composition for a combined use with radiotherapy.

Polymer nanoparticle injection formulation composition containing rapamycin with improved water solubility, preparation method thereof, and anticancer composition for combined use with radiotherapy

A sustained-release microparticle containing a poorly water-soluble drug is disclosed. The sustained-release microparticle containing a poorly water-soluble drug has a multivalent metal ion salt of polylactic acid having at least one terminal carboxyl group or a derivative thereof. The poorly water-soluble drug is entrapped in the multivalent metal ion salt of polylactic acid or a derivative thereof The polylactic acid has at least one terminal carboxyl group or a derivative thereof has an average molecular weight number from 500 to 5,000 daltons. A method for preparing a sustained-release polymeric microparticles containing a poorly water-soluble drug is provided.

Sustained-release polymeric microparticles containing poorly water-soluble drug and method for preparing the same

Disclosed are a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(&#x3b1;-hydroxy acid), and a method for preparing the same. The method for preparing a highly pure amphiphilic block copolymer including a hydrophobic polymer block of a poly(&#x3b1;-hydroxy acid) includes removing &#x3b1;-hydroxy acid, lactone monomers thereof, oligomers thereof and an organometal catalyst in polymerizing the amphiphilic block copolymer.

Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof

The present invention relates to an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block with a terminal hydroxyl group wherein the terminal hydroxyl group of the hydrophobic bock is substituted with a tocopherol or cholesterol group. It also relates to polymeric compositions capable of forming stable micelles in an aqueous solution, comprising the amphiphilic block copolymer and a polylactic acid derivative wherein one or more ends of the polylactic acid are covalently bound to at least one carboxyl group.

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Daejeon, South Korea

Bong Oh Kim