Agency for Science, Technology and Research

National University of Singapore

National University Hospital (Singapore) Pte. Ltd.

National University Hospital

Bok Yan So

Heng-phon Too

Lihan Zhou

Ruiyang Zou

Khay Guan Yeoh

Feng Zhu

Wei Peng Yong

Khay-Guan Yeoh

Disclosed are methods of determining the likelihood of a subject having or developing a gastric cancer. The methods comprise measuring the expression level of at least one miRNA having at least 90% sequence identity with an miRNA as described herein in a non-cellular biofluid sample obtained from the subject, wherein differential expression of miRNA expression in the sample obtained from the subject, as compared to a control, may be indicative of the subject having gastric cancer and wherein the miRNA may be either an miRNA listed as 'up-regulated' or an miRNA listed as 'down-regulated'. Also disclosed is a method of determining the likelihood of a subject having or developing a stage of a gastric cancer.

MicroRNA biomarker for the diagnosis and treatment of gastric cancer

Growing community of inventors

Singapore, Singapore

Bok Yan So