National Research Council of Canada

Other

Neuroarm Surgical Ltd.

Boguslaw Tomanek

Garnette Roy Sutherland

Tim Fielding

Perry Newhook

Jack Adam Tuszynski

Alexander Greer

Scott King

Jarod Matwiy

Calvin Bewsky

Vyacheslav Vlolovskyy

Mike Smith

Dorota Bartusik

John Torin Huzil

Jonathan Y Mane

The invention relates to colchicine derivatives, methods and uses thereof for treatment of cancer. In certain embodiments, the colchicine derivative comprises a compound of Formula I: 

Colchicine derivatives, methods and uses thereof

Methods, devices, and systems for use in accomplishing registration of a patient to a robot to facilitate image guided surgical procedures, such as stereotactic procedures.

Methods, devices, and systems useful in registration

To perform multinuclear magnetic resonance spectroscopy and imaging, a coil with a high signal-to-noise ratio and spatially uniform B field that covers the same volume of interest at several frequencies is preferred. A radio frequency surface coil probe that produces a homogeneous field within the same volume for both P and H is described. The probe provides signal to noise characteristics close to those of a single frequency double ring assembly. It acquired excellent proton images and P spectra from an image selected voxel in rat liver at 7 T. The probe uses a double ring construction where each ring is tuned by a parallel LC trap to two or more different frequencies. A calculation of the values of the inductance and capacitance allows the double coil arrangement to be tuned to the required frequencies with a peak of the homogeneity at each frequency occurring at the same distance from the coil and with good Q. The probe is powered by a driver coil adjacent to the probe by mutual inductance.

Multiple tunable double ring surface coil with high B1 homogeneity

Growing community of inventors

Calgary, Canada

Boguslaw Tomanek