Watson Laboratories Inc.

Assia Chemical Industries Ltd.

Bodkhe Arjun Rajaram

Anantha Rajmohan Muthusamy

Parven Kumar Luthra

Amit Singh

Joshi Ashutosh Vijay

Samala Rajamouli Srihari

Dolitzky Ben-Zion

Mendelovici Marioara

Mane Ganesh Shivaji

The present disclosure relates to novel processes for the preparation of short acting benzodiazepines as well as to novel intermediates in this process. More particularly the disclosure relates to processes and intermediates for preparation of Methyl 3-[(4S)-8-bromo-1-methyl-6-(pyridin-2-yl)-4H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propanoate, commonly known as Remimazolam. The present disclosure also relates to solid state forms of Remimazolam salts, processes for the preparation thereof, pharmaceutical formulations/compositions thereof, and methods of use thereof.

Process for the preparation of Remimazolam and solid state forms of Remimazolam salts

Process for the preparation of Remimazolam  and solid state forms of Remimazolam salts

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Thane, India

Bodkhe Arjun Rajaram