Hemodynamx-technologies Ltd.

Boaz Nishri

Tanhum Feld

Sagy Karavany

Menashe Yacoby

Apparatus and methods are described for regulating blood flow in an ascending aorta of a subject including inserting a device into the ascending aorta. When in a deployed state, the device defines an inner surface that defines a conduit through the device, at least a portion of the inner surface diverging, such that a cross-sectional area of the conduit at the downstream end of the diverging portion is greater than a cross-sectional area of the conduit at the upstream end of the diverging portion. The device is deployed within a longitudinal portion of the ascending aorta, such that the device defines the conduit throughout deployment of the device within the longitudinal portion of the ascending aorta. Other applications are also described.

Aortic implant

Apparatus and methods are described including inserting an implantable device () into a blood vessel of a subject while the implantable device is disposed inside a delivery device and is constrained in a constrained configuration by the delivery device. The implantable device is released from the delivery device into the blood vessel, thereby causing the implantable device to assume a non-constrained configuration by an upstream end of the implantable device radially expanding (), a central portion () of the implantable device radially expanding such that along the central portion of the implantable device the inner surface () of the implantable device defines a diverging portion () of a conduit (), and the implantable device forming a folded portion () between the upstream end of the implantable device and the central portion of the implantable device. Other applications are also described.

Apparatus and methods are described for regulating blood flow in an ascending aorta of a subject including inserting a device () into the ascending aorta. When in a deployed state, the device defines an inner surface () that defines a conduit () through the device, at least a portion () of the inner surface diverging, such that a cross-sectional area of the conduit at the downstream end () of the diverging portion is greater than a cross-sectional area of the conduit at the upstream end () of the diverging portion. The device is deployed within a longitudinal portion of the ascending aorta, such that blood flow through the portion of the ascending aorta, via any flow path other than through the conduit, is less than 20 percent of total blood flow through the portion of the ascending aorta. Other applications are also described.

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D.N. Menashe, Israel

Boaz Nishri