Ab Bofors

Landstingens Inkopscentral

Bo Thuresson Ekenstam

Karl G Claeson

Ralph Lennart Brattsand

Bror Arne Thalen

Erik G Nordqvist

A container for dispensing fluid and semifluid liquids and pastes, such as for medicinal use, is provided with a top flexible dome and a bottom dome which may or may not be flexible. The contents which are stored in the space between the two domes is squeezed outwardly through a spout on the bottom dome by pressing and forcing the top dome into the bottom dome. The container may be combined with other containers which are connected along flanges of each container, which flanges are used to grip the container by fingers so that when the top dome is pressed downwardly by a thumb the fingers may aid in the process. The plurality of containers connected along the flanges form a block which may be combined with other blocks for easy transport.

Container suitable for smaller quantities of fluid or semi-fluid

A process for the resolution of stereoisomeric mixtures of certain steroids obtained by synthesis into its components, comprising subjecting the stereoisomeric mixture to gel filtration, the components in view of different retention volumes being separated and being separately recoverable; and stereoisomeric components A and B thereby obtained, pharmaceutical compositions thereof; and method of treating inflammation therewith.

Novel stereoisomeric component A of stereoisomeric mixtures of

A process for the resolution of stereoisomeric mixtures of certain steroids obtained by synthesis into its components, comprising subjecting the stereoisomeric mixture to gel filtration, the components in view of different retention volumes being separated and being separately recoverable; and stereoisomeric components A and B thereby obtained, pharmaceutical compositions thereof; and method of treating inflammation therewith. This application claims pharmaceutical compositions and method of employing Component B of the novel steroid stereoisomeric mixtures, including both the free 21-hydroxyl and the 21-acetates thereof.

Compositions and method of treating with component B of stereoisomeric

Novel steroids having the general formula: ##SPC1## Wherein X and Y are independently selected from hydrogen and fluorine, X being selected from hydrogen and fluorine when Y is hydrogen and X being fluorine when Y is fluorine, Z is selected from hydroxyl and esterified hydroxyl preferably containing a maximum of 12 carbon atoms, if any, in the esterifying group, R is selected from straight and branched hydrocarbon chains having 2-10 carbon atoms; processes for the preparation of said steroids; compositions containing said steroids; and method of treating inflammation therewith. The steroids are physiologically active compounds possessing anti-inflammatory activity. This application claims pharmaceutical compositions and method of treating employing the novel steroid steroisomeric mixtures.

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Molndal, Sweden

Bo Thuresson Ekenstam