Biogaia Ab

Metabogen Ab

Bo Möllstam

Stefan Roos

Uma Nathan

Estelle Grasset

Muhammed Khan

Elisabeth SJÖBERG

Bengt BJÖRKSTEN

Eamonn Connolly

Bengt BJÖRKSTÉN

Fredrik Karlsson

Muhammad Khan

The invention relates to selection of bacterial strain for use in treating serotonin deficiency and/or a disease related to serotonin deficiency by culturing bacteria of a lactic acid producing bacterial strain, under aerobic conditions, in a culture medium comprising tryptophan. Any serotonin produced by the bacteria of the lactic acid producing bacterial strain in the culture medium is detected and the lactic acid producing bacterial strain is selected as effective in treating serotonin deficiency and/or a disease related to serotonin deficiency in a subject if serotonin is detected in the culture medium.

Serotonin producing bacteria

The present invention relates to lactic acid bacterial strains which are capable of producing or inducing the production of melatonin, for use in the production of melatonin in a subject. Preferred strains for such uses are capable of producing or inducing the production of adenosine. Therapeutic uses of such strains include the treatment or prevention of diseases associated with melatonin deficiency, for example infantile colic. Novel strains are also provided.

Selection and use of melatonin supporting bacteria to reduce infantile colic

The present invention generally relates to a strain ofprobiotic bacteria and a poultry vaccine for use in the in ovo vaccination of poultry, wherein said strain and said vaccine are administered to an embryonated poultry egg. Compositions suitable for use in an in ovo vaccination protocol for poultry comprising a strain ofprobiotic bacteria and a vaccine diluent which is suitable for the poultry vaccine to be used in said vaccination protocol are also provided, as are suitable kits for use in the invention.

In ovo delivery of probiotic cultures

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Lerum, Sweden

Bo Möllstam