University of Florida Research Foundation, Incorporated

Bo Lu

Guanghua Yan

Chihray Liu

Jonathan Gang Li

Yunmei Chen

Richard Helmig

Hao Zhang

Kathryn Elizabeth Mittauer

Chunjoo Park

A cranial alignment device for use in intracranial stereotactic radiotherapy includes a nosepiece that is custom shaped to mate with the dorsum and alae of the patient's nose.

Cranial alignment device for use in intracranial stereotactic surgery

A system for constructing images representing a 4DCT sequence of an object from a plurality of projections taken from a plurality of angles with respect to the object and at a plurality of times, first portions of the object being less static than second portions of the object. The system may comprise a processor configured to: iteratively process projections of the plurality of projections for a plurality of groups, each group comprising projections collected while the first portions of the object are in corresponding locations, with each iteration comprising: reconstructing first image portions representing the first portions of the object, the reconstructing of each first image portion of the first image portions being based on projections in a respective group of the plurality of groups; and reconstructing the second image portion, the second image portion representing the second portions of the object, based on projections in multiple groups of the plurality of groups and on the reconstructed first image portions.

Common-mask guided image reconstruction for enhanced four-dimensional cone-beam computed tomography

An ambiguity-free optical tracking system () includes a position sensor unit (), a control box (), a computer () and software. The position sensor unit includes two cameras (and) that track a plurality of individual infra-red reflecting markers () affixed on a patient's skin. Coordinates of the cameras in a coordinate system of the cameras are determined as part of a system calibration process by intentionally creating ambiguous markers with two true markers. Using this information, an ambiguity elimination algorithm automatically identifies and eliminates ambiguous markers. A recursive backtracking algorithm builds a one-to-one correspondence between reference markers and markers optically observed during treatment. By utilizing a concept of null markers, the backtracking algorithm deals with missing, misplaced and occluded markers.

Ambiguity-free optical tracking system

A patient safety system (PSS) () uses optical tracking in a linear accelerator treatment room to prevent gross setup errors. A patient () undergoes a computed tomography (CT) treatment-simulation scan while a CT ball bearing (BB) is on patient's surface. The CT BB is replaced with an infrared reflective marker (IRRM) () before radiotherapy treatment starts. Coordinates of the CT BB relative to an isocenter of the treatment room are used as reference for tracking. The coordinate system of an optical tracking system is converted to a coordinate system of the treatment room. The PSS evaluates setup accuracy for a radiotherapy session by comparing real-time position of the single IRRM determined by the optical tracking technology with a predicted reference position, and displays results on a graphical user interface. The PSS stops radiation when a deviation between real-time coordinates and predicted coordinates of the IRRM () exceeds a predefined threshold.

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Gainesville, FL, United States of America

Bo Lu