Pharmacia Ab

Pharmacia & Upjohn Ab

Bo B Gustafsson

Stefan Lundmark

Otto Skolling

Kjell Berglund

Cathrine Brooling

Karl-Erik Lundh

Carl O Danielson

Gote E Richardsson

A flexible transparent container for improved storage of oxygen sensitive parenterally administerable agents comprising an inner, primary container enclosed in a substantially oxygen impermeable outer envelope with an oxygen absorber, capable of consuming essentially all residual oxygen after the outer envelope is sealed, and for sufficient period also the oxygen penetrating said envelope. The inner container is made of a polypropylene containing flexible polymeric material compatible with lipophilic agents capable of forming both permanent and peelable seals, while the envelope is made of a substantially water impermeable flexible multilayered polymeric material comprising a first outer substantially water impermeable polymeric film with oxygen barrier forming capacity, assembled with a second, inner polymeric film with a supplementary oxygen barrier forming capacity. The container essentially maintains its characteristics after being subjected to sterilization by steam or radiation.

Containers for parenteral fluids

A closure device for fluid-tight closure of an opening of a fluid container. The device comprises a casing part (1) and a cap part (2). These parts are injection molded from different plastic materials, preferably from PVC and polypropylene, respectively, one partially against the other. A tubular portion (12) of the cap part (2) intrudes sealingly into a substantially cylindrical hollow space between an internal and an external sleeve portion (3,4) of the casing part (1).

Closure device

Growing community of inventors

Alunda, Sweden

Bo B Gustafsson