Pliva, Farmaceutska, Kemijska, Prehrambena I Kozmeticka Industrija,

Blanka Jamnicky

Miljenko Dumic

Darko Filic

Mladen Vinkovic

Mirela E Skinja

Mladen Vinkovi C

Darko Fili C

Miljenko Dumi C

Novel O-substituted or O-unsubstituted 6-sulfonamido-1,3-dioxepane-5-ols having hypoglycemic activity are obtained from 6-amino-1,3-dioxepane-5-ol, tetrahydro-6H-[1,3]-dioxepino[5,6-d]oxazole, 5,6-epoxy-1,3-dioxepane or N-sulfonyl-tetrahydro-1H,4H-[1,3]-dioxepino[5,6-b]azirine as starting materials.

Sulfonamidodioxepanes, methods of preparation, intermediates, salts and

Novel 1-(2-,3- or 4-hydroxylaminobenzensulfonyl-1a,2,6,6 a-tetrahydro-1H,4H-[1,3]-dioxepino[5,6-b]azirines with hypoglycemic activity are prepared by selective reduction of appropriate 1-(2-,3- or 4-nitrobenzenesulfonyl) derivatives.

Hydroxylamines with hypoglycemic activity

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Zagreb, Croatia

Blanka Jamnicky