The Mclean Hospital Corporation

Blaise deB Frederick

Perry F Renshaw

Lawrence Leroy Wald

Michael L Rohan

Luis C Maas, Iii

Ronald L Cowan

The invention involves an active phantom that transmits a waveform based on data reflecting free induction decay signals. The methods and apparatuses of the invention can be used, for example, to test and calibrate a magnetic resonance scanner; evaluate image acquisition parameters and reconstruction algorithms; and train scanner operators. In addition, the invention can simulate complex samples, e.g., a human brain without requiring human subject available to submit to the time and discomfort of a magnetic resonance scan.

Generation of synthetic nuclear magnetic resonance signals

The invention provides methods for assessing central nervous system function and diagnosing central nervous system disorders in a human, and for evaluating therapeutic agents that affect central nervous system neurotransmitter function. The invention uses cortical imaging methods to assess changes in visual system processing, and correlates these changes to central nervous system function.

Method for assessing cortical response to blue light

The design and construction of a novel phased array echoplanar receiver system for magnetic resonance imaging for use with a standard clinical EPI system is described, and in vivo results showing increased SNR are presented.

Phased array echoplanar imaging system for fMRI

Registration of images includes rotational and translation correction. Rotational correction includes estimating a rotational-correction angle by polar K-space cross-correlation. K-space regridding is used to rotate an image by the estimated correction angle. Translational correction is obtained by K-space phase-plane conjugation.

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Watertown, MA, United States of America

Blaise deB Frederick