Other

Headwall Photonics, Inc.

Blair K Simon

David P Bannon

Domhnull Granquist-Fraser

Paul Bartel

Carson Roberts

Kevin M Didona

A device and system for non-invasively measuring wavelength-dependent changes in optical absorption of brain tissue damaged by CTE, TBI, concussion, repetitive trauma, and/or Lou Gehrig's disease in comparison to signals from healthy normal tissue for a subject in vivo. The brain, tissues, and fluids superficial to the brain are trans-cranially illuminated by light source(s) in low-absorption spectral windows for tissue in the visible and/or near-infrared parts of the spectrum. Optode(s) are disposed at predetermined radial distance(s) from a light output to collect the scattered and/or deflected signal from the surface of the head. The predetermined radial distance from the light output to the optode is correlated with the depth of tissue penetration for the light collected by the optode. A spectrometer and computer analyze the collected light for characteristic optical signatures of the brain tissue damage utilizing the absorbance and/or reflectance and/or transmission spectra generated as a result.

Diagnostic system and methods for simultaneously detecting light at multiple detection locations in a spectroscopic system

From a sample image, a fertilization test method determines the ratio of fertilized cells in the image by identifying cells in the image and calculating cell properties for each cell. An area is determined between a cell body and an outer search limit to search for a fertilization membrane. A cell outline is defined for each cell and cell membrane edges are found within the search area by changing the cell outline size between the cell body boundary the outer search limit, checking for a match with detected cell membrane edges. A cell is determined to be fertilized based on matches between detected cell membrane edges and the cell outline, patterns of contrast changes indicated by a cell membrane, or circles fit to cell membrane edges.

Fertilization test method and apparatus

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Clinton, MA, United States of America

Blair K Simon