Cytiva Sweden Ab

Ge Healthcare Bioprocess R&d Ab

Bjorn Johan Lundgren

Klaus Gebauer

Ola Lind

Kajsa Stridsberg-Friden

Jamil Shanagar

Ann-Christin Magnusson

Raf Lemmens

Emmanuel Macedo

Lena Maria Sandberg

Elisabeth Hallgren

Helena Widegren

The present invention relates to a method and system for aseptic material transfer from a storage container to a bioreactor. More precisely the invention relates to a method and system for aseptically transferring dry material, such as microcarriers for cell cultivation, to a bioreactor, comprising transferring microcarriers from a first container housing said microcarriers to a bioreactor for cell cultivation via r transfer tubing connecting the first container to the bioreactor, wherein the transfer is accomplished with pressurized air or gas supplied to the container.

Method and system for cell cultivation

The invention provides a packing method for high efficiency chromatography columns starting from dry swellable particles, as well as columns packed by the method and the use of the columns in separation of biomolecules. In the packing method, an amount of dry swellable particles sufficient to give a swollen volume in a liquid of about 105-120% of the column chamber volume is transferred to the column, the column is closed and the liquid is provided to the column.

Method for dry packing chromatography columns

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Uppsala, Sweden

Bjorn Johan Lundgren