Wenzhou Medical University

Bixin Zeng

Min Xu

Weihao Lin

Xinlin Chen

Zili Cao

An optical imaging method based on mapping of a layered structure. The specific spatial distribution and optical properties of materials in each layer are fully taken into account so that optical information of each corresponding layer can be separated out, wherein the optical information comprises absorption and scattering coefficients of each layer. The method is applied to biological system detection to obtain physiological parameter information of each layer of tissue, wherein the physiological parameter information comprises the content of oxyhemoglobin, the content of deoxyhemoglobin the content of melanin, and epidermal thickness. The method in combination with SFDI technology is applied to forearm reactive hyperemia experiments and skin mole examinations yielding positive results.

Optical imaging method based on mapping of layered structure

A single snapshot multi-frequency demodulation method for a modulated image obtained by modulating and summing one or more original components at different frequencies in a time domain or spatial domain, especially for a modulated image including multiple frequency components. AC and DC component values of each pixel at each frequency are extracted sequentially, and then an original AC and DC component image corresponding to each frequency is obtained. The method can be used in the time or spatial domain, can decompose multiple frequency component images using single measurement, has the advantages of fast speed, higher demodulation precision and good de-noising effect, meets the requirements for acquiring multiple pieces of frequency information at a time and overcomes inevitable errors in multiple measurements. Further, multiple pieces of image information can also be transmitted once using the demodulation method, so that parallel real-time transmission of the information in the communication field is realized.

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Wenzhou, China

Bixin Zeng