Transmural Systems LLC

National Institutes of Health, a Component of the US Dept. of Health & Human Services

Biwei MacDonald

Nasser Rafiee

Stuart MacDonald

Alana Rafiee

Robert J Lederman

Kanishka Ratnayaka

Koosha Rafiee

Morgan House

Mai Le Diep

The disclosure provides various embodiments of systems to facilitate the cutting of tissue structures and other tissue structures percutaneously.

Catheter and actuator systems and methods

In some implementations, a radially self-expanding endograft prosthesis is provided that includes (i) distal flange that is self-expanding and configured to flip generally perpendicularly with respect to a body of the prosthesis to help seat the prosthesis against a tissue wall, (ii) a distal segment extending proximally from the distal flange that has sufficient stiffness to maintain a puncture open that is formed through a vessel wall (iii) a compliant middle segment extending proximally from the distal segment, the middle segment being more compliant than the distal segment, and having independently movable undulating strut rings attached to a tubular fabric, the combined structure providing flexibility and compliance to allow for full patency while flexed, the segment being configured to accommodate up to a 90 degree bend, (iv) a proximal segment having a plurality of adjacent undulating strut rings that are connected to each other.

Devices and methods for effectuating percutaneous shunt procedures

Devices and methods for effectuating percutaneous glenn and fontan procedures

Devices and methods for effectuating percutaneous Glenn and Fontan procedures

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Andover, MA, United States of America

Biwei MacDonald