Acadia Pharmaceuticals Inc.

Birgitte Winther Lund

Roger Olsson

Magnus Gustafsson

Lene Hyldtoft

Fabrice Piu

Nathalie Schlienger

Mikkel Boas Thygesen

Jan Pawlas

Vladimir Sherbukhin

Fabrizio Badalassi

Rasmus Lewinsky

Alma Fejzic

Disclosed herein are methods of treatment and prevention of diseases and disorders related to estrogen receptors comprising administering novel di-aromatic compounds to patients in need thereof.

Compounds with activity at estrogen receptors

Disclosed herein are compounds of Formula I as disclosed herein, methods of modulating the activity of an estrogen receptor and methods of treating a disorder associated with estrogen receptors.

Disclosed herein are novel di-aromatic compounds and methods for using various di-aromatic compounds for treatment and prevention of diseases and disorders related to estrogen receptors.

Disclosed herein is a novel class of aminophenyl compounds having the structure: wherein Ris cyano or nitro and ring A is a bi- or tricyclic bridged heterocycle and to their use as modulators of androgen receptor for the treatment or prevention of conditions relating thereto.

Aminophenyl derivatives as selective androgen receptor modulators

Disclosed herein are bicycloaryl compounds of Formula (I) that selectively modulate nuclear receptors, preferably the androgen receptor, or a pharmaceutically acceptable salt, ester, amide, or prodrug thereof, and methods of treating disease comprising administering a compound of Formula (I) to a patient in need thereof.

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Bagsvaerd, Denmark

Birgitte Winther Lund