Novo Nordisk A/s

Ferring B.v.

Birgitte Nissen

Patrick William Garibay

Flemming Seier Nielsen

Birgitte Schjellerup Wulff

Betty L Pedersen

Andreas Vegge

Tue Hansen

Carsten Hoeg-Moller

Helle Poulsen

Crilles Casper Larsen

Jorgen Wittendorff

Kenneth Manby Pedersen

Søren ØStergaard

Betty Lomstein Pedersen

The invention relates to pharmaceutical compositions comprising a peptide, such as a GLP-1 peptide and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid. The invention further relates to processes for the preparation of such compositions, and their use in medicine.

Solid compositions comprising a GLP-1 agonist and a salt of N-(8-(2-hydroxybenzoyl)amino)caprylic acid

The present invention relates to solid pharmaceutical compositions for oral administration comprising a GLP-1 agonist, an absorption enhancer which is a salt of medium-chain fatty acid, and an enteric coating as well as uses thereof.

Tablets comprising GLP-1 agonist and enteric coating

Disclosed are improved granular pharmaceutical preparations, together with improved methods and apparatus for preparation of granules for use in such preparations. Such methods are especially useful for making granules for solid oral dose pharmaceutical preparations, and are particularly suited to the production of granules comprising 5-aminosalicylic acid (5-ASA) for the treatment of inflammatory bowel disease. The granules exhibit a more sharply peaked length distribution, and hence aspect ratio distribution, and have a consequently much sharper dissolution profile after further processing.

Granules for pharmaceutical preparations, methods and apparatus for their production

Growing community of inventors

Glostrup, Denmark

Birgitte Nissen