Nuvelo, Inc.

Kirin Beer Kabushiki Kaisha

Birgit Stache-Crain

Radoje Drmanac

Lewis T Williams

Giulia C Kennedy

Snezana Drmanac

Michael A Innis

Klaus Giese

David B Kita

Christoph Reinhard

Jaime A Escobedo

Filippo M Randazzo

David Pot

Pablo Dominguez Garcia

Ivan Labat

George Lamson

Altaf Kassam

Julie Sudduth-Klinger

Radomir Crkvenjakov

Mark Dickson

Dena Leshkowitz

Veronica Garcia

Lee William Jones

Y Tom Tang

Mitsuo Nishikawa

Juhi Lee

Ivan Lobal

A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells which do not support the proliferation or survival. Proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is supported by using stromal cells in which the isolated gene is expressed or a gene product of the isolated gene.

Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same

This invention relates to novel human polynucleotides and variants thereof, their encoded polypeptides and variants thereof, to genes corresponding to these polynucleotides and to proteins expressed by the genes. The invention also relates to diagnostic and therapeutic agents employing such novel human polynucleotides, their corresponding genes or gene products, e.g., these genes and proteins, including probes, antisense constructs, and antibodies.

Human genes and gene expression products V

Human genes and gene expression products II

Growing community of inventors

Sunnyvale, CA, United States of America

Birgit Stache-Crain