University of Houston System

Instituto Tecnologico Y De Estudios Superiores De Monterrey

Binh V Vu

Richard C Willson, Iii

Mary A Crum

Richard Coale Willson

Marco Antonio Rito Palomares

Federico Augusto Ruiz Ruiz

Federico Augusto Ruiz-Ruiz

Jinsu Kim

Ekaterini Kourentzi

Ujwal Patil

Olga Patricia Vázquez Villegas

Victoria M Hlavinka

The present disclosure relates to the detection of analytes in high volumetric flow applications. Particular embodiments relate to the use of fluorescence polarization/anisotropy based for detection of analytes in a flow cell. In one testing format, an analyte of interest is probed with reagents containing fluorescent labeled recognition elements. When present in a sample or portion of a sample, the labeled analyte produces a shift in fluorescence polarization/anisotropy/intensity/lifetime as the output signal following the binding of the recognition elements to the analytes.

Systems and method for detection of analytes in high volumetric flow applications

Disclosed are methods and kits for analyzing a sample comprising 1,5-anhydroglucitol and a possible first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte. Also provided are kits including reagents for practicing the claimed methods.

Chemical detection assays

Methods, devices and kit for analyzing a sample comprising 1,5-anhydroglucitol and a first analyte via one or more chemiluminescent reactions. Certain embodiments include measuring a first light response resulting from a first chemiluminescent reaction and measuring a second light response resulting from a second chemiluminescent reaction. Certain embodiments also include comparing the first light response to the second light response to determine a ratio of 1,5-anhydroglucitol and the first analyte.

Systems and methods for detection of chemtiluminescent reactions

Growing community of inventors

Houston, TX, United States of America

Binh V Vu