Gm Global Technolgoy Operations, Inc.

Shandong Danhong Pharmaceutical Co., Ltd.

Bing Deng

Jenne-tai Wang

Qi Liu

Dorel M Sala

Yong Xia

Qing Zhou

Chin-Hsu Lin

Mark O Neal

Fan Bai

Donald K Grimm

Shuhui Chen

Gary Lee Jones

Wentao Wu

Mark A Kramarczyk

James F Pywell

Zhixiang Li

David A Craig

Martin A Hogan

Jiang L Du

Janet S Goings

Jiahu Wu

Margaret M Andreen

Daniel Shakespear

Vincent Barrett Walkup

Corey Pickering

Melissa Faustich

Disclosed are a sustained release suspension containing dezocine analogue ester and a preparation method therefor. According to the present invention, an injectable oily auxiliary material which may pharmaceutically serve as a sustained-release depot and an excipient are selected, and micronization technology is used jointly with high pressure homogenization technology and an anti-solvent technique to prepare an injectable long-acting suspension. The main components of the suspension are a compound represented by formula (I), the injectable oil, and the like. 

Sustained release suspension containing dezocine analogue ester and preparation method therefor

A system for determining and executing an autonomous-vehicle vehicle travel route, including a hardware-based processing unit and a non-transitory computer-readable storage medium. The storage medium includes an input-interface module that, when executed by the hardware-based processing unit, obtains factor data indicating factors relevant to determining a vehicle travel route. The storage medium also includes a route-generation module comprising a route-complexity sub-module. The route-complexity sub-module determines, based on the factor data, route-complexity indexes corresponding to respective optional routes. The route-generation module determines the vehicle travel route based on the route-complexity indexes. The storage in various embodiments includes other sub-modules associated with other elements, such as autonomous-driving safety, comfort, stress, pollution, scenery, or infrastructure-accessibility, for determining and executing an autonomous-driving travel route. In some embodiments, the storage includes an autonomous-driving perceptions module and an autonomous-driving control module for modifying vehicle functions in executing the autonomous-driving travel route.

Systems for autonomous vehicle route selection and execution

Methods and apparatus are provided for navigation of a vehicle. In one embodiment, a navigation system includes: a map database, and a navigation processor. The map database includes a map layer of autonomous road data, and at least one other layer of map data. The navigation processor is configured to determine a route for a vehicle to a destination preferring use of autonomous roads according to a setting for preferring use of autonomous roads and based on the map layer of autonomous road data and the at least other layer of map data; and display a display map for a vehicle through a navigation display unit including highlighting autonomous roads on the navigation display unit, based on the map layer of autonomous road data, together with the at least one other layer of map data.

Methods and systems to convey autonomous/semi-autonomous feature available roadways

A method for controlling vehicle procession through an intersection includes monitoring movement of a first vehicle through the intersection, and synchronizing movement of a second vehicle following the first vehicle through the intersection to the first vehicle movement through the intersection.

Vehicle procession control through a traffic intersection

A method and system are provided for planning a route for a vehicle from a starting point to a destination. The method includes the steps of generating a plurality of routes based on a non-safety factor; evaluating the plurality of routes based on a safety factor; selecting a first route from the plurality of routes based on the safety factor; generating driving instructions based on the first route; displaying the first route on a display device.

Systems and methods for planning vehicle routes based on safety factors

A system and method for classifying the optimization of safety features on a vehicle for a driver of the vehicle based on the height and mass of the driver. The method includes determining a number of basic driver sizes based on driver height and mass and determining a driver's seat position for each basic driver height. The method also identifies a set of tunable design variables that are used to adjust the safety features of the vehicle and performs design optimization analysis to identify an optimal design for the vehicle safety features for each of the basic driver sizes. The method then identifies the design from the optimal designs that provides the best performance for randomly selected reference drivers and classifies all drivers into a predetermined number of classifications where each classification represents a particular optimal design.

Performance-based classification method and algorithm for drivers

A vehicle includes at least one reconfigurable system having a plurality of selectively variable parameters, and a controller that is operatively connected to the at least one reconfigurable system to control the values of the plurality of selectively variable parameters. The controller is also configured to receive data indicative of physical characteristics of a person from at least one data storage medium, and configured to determine values of the selectively variable parameters according to a predetermined algorithm based on the data indicative of physical characteristics of a person. The controller is also configured to cause the selectively variable parameters to assume the determined values.

Vehicle personalization system

A driver drowsiness mitigation system of a vehicle includes a driver impairment detection system for detecting drowsiness of a driver of the vehicle. A plurality of alert devices is provided for countering a drowsiness of the driver of the vehicle. A controller enables at least one of the alert devices when a drowsiness of the driver is detected. A prioritized order for enabling respective alert devices is selectively configurable within the controller according to the identity of the driver.

Driver configurable drowsiness prevention

A seat assembly for a vehicle includes a lower seat portion and a seatback portion. The seatback portion is selectively movable to vary the reclination angle of the seatback portion. The seat assembly is configured so that a first part of the lower seat portion rises relative to a second part of the lower seat portion so that the lower seat portion acts as an occupant restraint when a predetermined condition exists. Exemplary predetermined conditions include the reclination angle changing, the reclination angle exceeding a predetermined amount, and conditions indicative of an elevated risk of vehicle impact.

Vehicle seat assembly

A vehicle includes an energy absorber that is positionable rearward of a passenger seat to absorb energy from a force having a forward component and being directed toward the rear surface of the passenger seat. In one exemplary embodiment, the energy absorber is a cellular material. In another exemplary embodiment, the energy absorber is a selectively inflatable cushion. A corresponding seat assembly is also provided.

Energy absorption systems for vehicles

An energy-absorbing hood assembly for a vehicle includes upper and lower layers and a middle panel. The upper and lower layers have first and second interface surfaces, respectively. The middle panel has opposing first and second surfaces defining a corrugated profile having a plurality of bonding surfaces, the bonding surfaces being attached to the first and second interface surfaces to thereby define a plurality of laterally oriented channels. The corrugated profile further defines a height and wavelength along a substantial portion of the hood assembly, each being configured to be variably tunable to provide different predetermined levels of absorption and attenuation of kinetic energy imparted to the hood assembly by objects upon impact therebetween. Preferably, the hood assembly also includes an upper hood panel having an inner surface secured to the upper layer. Ideally, the corrugated profile is a trapezoidal waveform profile.

Vehicle hood with sandwich inner structure

An energy-absorbing hood assembly for a vehicle includes upper, lower, and middle panels. The upper and lower panels respectively include first and second interface surfaces. The upper panel is preferably secured to an inner surface of an outer panel. The middle panel has opposing first and second surfaces defining an asymmetric waveform profile, preferably having a polygonal geometry. The middle panel member is secured to the first and second interface surfaces at preselected locations along the upper and lower surfaces, thereby defining a plurality of laterally oriented asymmetric channels. The asymmetric waveform profile is configured with distinct amplitudes and wavelengths along different regions of the hood assembly, each configured to provide different predetermined levels of absorption and attenuation of kinetic energy imparted to the hood assembly by objects upon impact therebetween. Ideally, the lower and middle panels are respectively configured to controllably fail at first and second predetermined crush loads.

Energy absorbing vehicle hood assembly with asymmetric sandwich inner structure

An energy-absorbing hood assembly for a vehicle includes an inner layer operatively secured to an upper layer having a first interface surface. The inner layer has opposing first and second surfaces defining a sinusoidal profile that is oriented to extend from the forward end of the vehicle towards the rearward end of the vehicle. The sinusoidal profile includes varying amplitudes and wavelengths along different regions of the hood assembly. The amplitudes and wavelengths are individually configured to provide regionally distinct predetermined levels of absorption and attenuation of kinetic energy imparted to the hood assembly by an object upon impact therebetween. Preferably, the hood assembly also includes a lower layer having a second interface surface; wherein the inner layer has a plurality of bonding surfaces attached to the first and second interface surfaces to thereby define a plurality of laterally oriented channels.

Vehicle hood assembly with rippled cushion support

A restraint system for restraining a recumbent occupant of a vehicle seat surface includes a member being selectively movable between a stowed position and a deployed position. The member, when in the deployed position, extends higher than the seat surface and is configured to exert a reaction force on the recumbent occupant to retain the occupant above the seat surface in the event of a vehicle impact.

Growing community of inventors

Rochester Hills, MI, United States of America

Bing Deng