National Taiwan University

Bing-Ching Ho

Pan-Chyr Yang

Sung-Liang Yu

Hsuan-Yu Chen

Gee-Chen Chang

Ker-Chau Li

Chun-Nan Lee

Disclosed herein is a method of determining whether a subject having or is at risk of developing lung cancer. The presence of the SNP locus of rs193100333, which corresponds to a mutation on YAP1 protein with a substitution of an arginine to a tryptophan at position 331, indicates the subject has or is at risk of developing lung cancer. Accordingly, also disclosed herein is a kit for facilitating the detection of the SNP locus of rs193100333.

Method or kit for determining lung cancer development

Treatment of picornavirus infection by inhibiting miR-141 activity. Also disclosed herein are a method for identify miR-141 inhibitory compounds and a method for identifying a target viral infection to be treated by anti-miR-141 therapy.

Treating picornavirus infection by targeting MicroRNA miR-141

Growing community of inventors

Taipei, Taiwan

Bing-Ching Ho